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3'-nucleotidase activity

Known as: 3'-mononucleotidase activity, 3'-phosphatase activity, 3' nucleotidase activity 
Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate. [EC:3.1.3.6]
National Institutes of Health

Papers overview

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2019
2019
Detection of DNA 3'-phosphatase activity based on exonuclease III-assisted cascade recycling amplification reaction.
DNA 3'-phosphatase is an essential enzyme, which plays a pivotal role in repairing DNA damage. The peculiar activity of DNA 3… Expand
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2011
2011
The role of human DNA glycosylase NEIL 2 and the single-strand break repair protein polynucleotide kinase 3 '-phosphatase in maintenance of the mitochondrial genome
The repair of reactive oxygen species (ROS)-induced base lesions and single-strand breaks (SSBs) in the nuclear genome via the… Expand
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2009
2009
DNA 3'-phosphatase activity is critical for rapid global rates of single-strand break repair following oxidative stress.
Oxidative stress is a major source of chromosome single-strand breaks (SSBs), and the repair of these lesions is retarded in… Expand
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2002
2002
Mutational analysis defines the 5'-kinase and 3'-phosphatase active sites of T4 polynucleotide kinase.
T4 polynucleotide kinase (Pnk) is a bifunctional 5'-kinase/3'-phosphatase that aids in the repair of broken termini in RNA by… Expand
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2001
2001
Domain structure and mutational analysis of T4 polynucleotide kinase.
T4 polynucleotide kinase (Pnk) is the founding member of a family of 5'-kinase/3'-phosphatase enzymes that heal broken termini in… Expand
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1999
1999
Purification of a polynucleotide kinase from calf thymus, comparison of its 3'-phosphatase domain with T4 polynucleotide kinase, and investigation of its effect on DNA replication in vitro.
Mammalian polynucleotide kinases (PNKs) carry out 5'-phosphorylation of nucleic acids. Although the cellular function(s) of these… Expand
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1989
1989
Delta-elimination in the repair of AP (apurinic/apyrimidinic) sites in DNA.
[5'-32P]pdT8d(-)dT7, containing an AP (apurinic/apyrimidinic) site in the ninth position, and [d(-)-1',2'-3H, 5'-32P]DNA… Expand
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1988
1988
Further purification and characterization of the DNA 3'-phosphatase from rat-liver chromatin which is also a polynucleotide 5'-hydroxyl kinase.
The DNA 3'-phosphatase activity of rat-liver chromatin has been purified. A DNA 5'-hydroxyl kinase activity comigrates at each… Expand
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1986
1986
Purification of S1 nuclease to homogeneity and its chemical, physical and catalytic properties.
An S1 nuclease preparation was used to purify the enzyme to homogeneity. The enzyme had an isoelectric point of 4.2, and a high… Expand
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Highly Cited
1977
Highly Cited
1977
3'-Phosphatase activity in T4 polynucleotide kinase.
The purification of T4 polynucleotide kinase results in the copurification of an activity which will specifically remove the 3… Expand
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