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3'-nucleotidase activity

Known as: 3'-mononucleotidase activity, 3'-phosphatase activity, 3' nucleotidase activity 
Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate. [EC:3.1.3.6]
National Institutes of Health

Papers overview

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2019
2019
Detection of DNA 3'-phosphatase activity based on exonuclease III-assisted cascade recycling amplification reaction.
2013
2013
Synthetic Lethal Targeting of PTEN-Deficient Cancer Cells Using Selective Disruption of Polynucleotide Kinase/Phosphatase
A recent screen of 6,961 siRNAs to discover possible synthetic lethal partners of the DNA repair protein polynucleotide kinase… 
2011
2011
The role of human DNA glycosylase NEIL 2 and the single-strand break repair protein polynucleotide kinase 3 '-phosphatase in maintenance of the mitochondrial genome
The repair of reactive oxygen species (ROS)-induced base lesions and single-strand breaks (SSBs) in the nuclear genome via the… 
Highly Cited
2007
Highly Cited
2007
Human polynucleotide kinase participates in repair of DNA double-strand breaks by nonhomologous end joining but not homologous recombination.
Human polynucleotide kinase (hPNK) is a bifunctional enzyme possessing a 5'-DNA kinase activity and a 3'-phosphatase activity… 
1999
1999
Purification of a polynucleotide kinase from calf thymus, comparison of its 3′‐phosphatase domain with T4 polynucleotide kinase, and investigation of its effect on DNA replication in vitro
Mammalian polynucleotide kinases (PNKs) carry out 5′‐phosphorylation of nucleic acids. Although the cellular function(s) of these… 
1993
1993
Altered fidelity of a nucleic acid modifying enzyme, T4 polynucleotide kinase, by safrole-induced DNA damage.
Mouse liver DNA adducted with metabolites of the spice constituent safrole (1-allyl-3,4-methylenedioxybenzene), when analyzed via… 
1990
1990
High ionic strength promotes selective 3'-phosphatase activity of T4 polynucleotide kinase.
1988
1988
Further purification and characterization of the DNA 3'-phosphatase from rat-liver chromatin which is also a polynucleotide 5'-hydroxyl kinase.
The DNA 3'-phosphatase activity of rat-liver chromatin has been purified. A DNA 5'-hydroxyl kinase activity comigrates at each… 
1986
1986
Purification of S1 nuclease to homogeneity and its chemical, physical and catalytic properties.
Highly Cited
1985
Highly Cited
1985
Enzyme regulation in a trypanosomatid: effect of purine starvation on levels of 3'-nucleotidase activity.
Crithidia fasciculata, a nonpathogenic relative of the leishmanial and trypanosomal pathogens of humans and animals, showed a 3… 
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