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3'-nucleotidase activity

Known as: 3'-mononucleotidase activity, 3'-phosphatase activity, 3' nucleotidase activity 
Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate. [EC:3.1.3.6]
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
DNA 3′-Phosphatase Activity Is Critical for Rapid Global Rates of Single-Strand Break Repair following Oxidative Stress
ABSTRACT Oxidative stress is a major source of chromosome single-strand breaks (SSBs), and the repair of these lesions is… Expand
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Highly Cited
2002
Highly Cited
2002
Mutational analysis defines the 5'-kinase and 3'-phosphatase active sites of T4 polynucleotide kinase.
T4 polynucleotide kinase (Pnk) is a bifunctional 5'-kinase/3'-phosphatase that aids in the repair of broken termini in RNA by… Expand
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Highly Cited
2001
Highly Cited
2001
Domain Structure and Mutational Analysis of T4 Polynucleotide Kinase*
T4 polynucleotide kinase (Pnk) is the founding member of a family of 5′-kinase/3′-phosphatase enzymes that heal broken termini in… Expand
1999
1999
Purification of a polynucleotide kinase from calf thymus, comparison of its 3′‐phosphatase domain with T4 polynucleotide kinase, and investigation of its effect on DNA replication in vitro
Mammalian polynucleotide kinases (PNKs) carry out 5′‐phosphorylation of nucleic acids. Although the cellular function(s) of these… Expand
1993
1993
Altered fidelity of a nucleic acid modifying enzyme, T4 polynucleotide kinase, by safrole-induced DNA damage.
Mouse liver DNA adducted with metabolites of the spice constituent safrole (1-allyl-3,4-methylenedioxybenzene), when analyzed via… Expand
1990
1990
High ionic strength promotes selective 3'-phosphatase activity of T4 polynucleotide kinase.
 
1989
1989
Delta-elimination in the repair of AP (apurinic/apyrimidinic) sites in DNA.
[5'-32P]pdT8d(-)dT7, containing an AP (apurinic/apyrimidinic) site in the ninth position, and [d(-)-1',2'-3H, 5'-32P]DNA… Expand
1988
1988
Further purification and characterization of the DNA 3'-phosphatase from rat-liver chromatin which is also a polynucleotide 5'-hydroxyl kinase.
The DNA 3'-phosphatase activity of rat-liver chromatin has been purified. A DNA 5'-hydroxyl kinase activity comigrates at each… Expand
1986
1986
Purification of S1 nuclease to homogeneity and its chemical, physical and catalytic properties.
An S1 nuclease preparation was used to purify the enzyme to homogeneity. The enzyme had an isoelectric point of 4.2, and a high… Expand
Highly Cited
1977
Highly Cited
1977
3'-Phosphatase activity in T4 polynucleotide kinase.
The purification of T4 polynucleotide kinase results in the copurification of an activity which will specifically remove the 3… Expand
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