3',5'-dichloromethotrexate

Known as: Dichloroamethopterin, 3',5'-Dichloroamethopterin, N-[3,5-Dichloro-4-[(2,4-diamino-6-pteridinylmethyl)methylamino]benzoyl] Glutamic Acid 
A chlorinated methotrexate derivative. Dichloromethotrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2017
05101519592017

Papers overview

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2012
2012
The aim of this paper is twofold: first, to introduce a neural field model motivated by a well-known neural mass model; second… (More)
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2010
2010
Sensitivity, specificity, and reproducibility are vital to interpret neuroscientific results from functional magnetic resonance… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Intracoronary administration of bone marrow-derived progenitor cells (BMC) was shown to improve coronary microvascular… (More)
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2009
2009
BACKGROUND In vitro data suggest that changes in myocardial substrate metabolism may contribute to impaired myocardial function… (More)
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2006
2006
Left ventricular (LV) torsion plays an important role in squeezing the blood out of the heart. To characterize the systolic… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES We sought to explore the relationship between a Tcap gene (TCAP) abnormality and cardiomyopathy. BACKGROUND… (More)
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1998
1998
OBJECTIVE To test the long-term effect of enalapril maleate treatment on progression of clinical signs of heart disease in dogs… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Dilated cardiomyopathy (DCM) is associated with a high incidence of malignant ventricular arrhythmias and sudden death… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Little is known about the characteristics of the inwardly rectifying K+ channel (IK1) and the influence of preexisting… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Myocardial blood flow (MBF) impairment has been documented in advanced dilated cardiomyopathy (DCM) in which… (More)
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