264W 94

Known as: 264W94 
 
National Institutes of Health

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Thiazepines

Papers overview

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2013
2013
Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.
The apical sodium-dependent bile acid transporter (ASBT) transports bile salts from the lumen of the gastrointestinal (GI) tract… (More)
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2012
2012
Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes.
Bile acids are recognized as metabolic modulators. The present study was aimed at evaluating the effects of a potent Asbt… (More)
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2002
2002
Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94.
264W94 was designed to inhibit the ileal bile acid transporter (IBAT). Evaluated in vitro, 264W94 dose-dependently inhibited… (More)
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Highly Cited
1999
Highly Cited
1999
Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats.
The relationship between biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats was examined. The biliary… (More)
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