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264W 94
Known as:
264W94
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Thiazepines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
[The inhibitors of the apical sodium-dependent bile acid transporter (ASBT) as promising drugs].
E. Saveleva
,
E. S. Tyutrina
,
T. Nakanishi
,
I. Tamai
,
A. Salmina
Biomeditsinskaia khimiia
2020
Corpus ID: 220074270
Inhibition of the apical sodium-dependent bile acid transporter (ASBT, also known as IBAT - ileal bile acid transporter, SLC10A2…
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Highly Cited
2013
Highly Cited
2013
Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes.
Yulin Wu
,
C. Aquino
,
+22 authors
J. Collins
Journal of Medicinal Chemistry
2013
Corpus ID: 207231598
The apical sodium-dependent bile acid transporter (ASBT) transports bile salts from the lumen of the gastrointestinal (GI) tract…
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Highly Cited
2012
Highly Cited
2012
Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes.
Lihong Chen
,
X. Yao
,
+11 authors
B. Gedulin
American Journal of Physiology. Endocrinology and…
2012
Corpus ID: 12280462
Bile acids are recognized as metabolic modulators. The present study was aimed at evaluating the effects of a potent Asbt…
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Highly Cited
2002
Highly Cited
2002
Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94 DOI 10.1194/jlr.M200121-JLR200
C. Root
,
Chari D Smith
,
S. Sundseth
,
H. Pink
,
Joan G. Wilson
,
M. Lewis
Journal of Lipid Research
2002
Corpus ID: 21773799
264W94 was designed to inhibit the ileal bile acid transporter (IBAT). Evaluated in vitro, 264W94 dose-dependently inhibited…
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Highly Cited
1999
Highly Cited
1999
Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats.
X. Liu
,
J. Chism
,
E. LeCluyse
,
K. Brouwer
,
K. Brouwer
Drug Metabolism And Disposition
1999
Corpus ID: 26124766
The relationship between biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats was examined. The biliary…
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