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25-hydroxycholesterol 7alpha-hydroxylase activity
Known as:
cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
, CYP7B1 oxysterol 7alpha-hydroxylase activity
, CYP7B1
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Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene…
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National Institutes of Health
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1 relation
CYP7B1 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Aerobic Exercise Training Selectively Changes Oxysterol Levels and Metabolism Reducing Cholesterol Accumulation in the Aorta of Dyslipidemic Mice
G. Ferreira
,
P. R. Pinto
,
+7 authors
M. Passarelli
Frontiers in Physiology
2017
Corpus ID: 23414077
Background: Oxysterols are bioactive lipids that control cellular cholesterol synthesis, uptake, and exportation besides…
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Highly Cited
2012
Highly Cited
2012
Oxysterol gradient generation by lymphoid stromal cells guides activated B cell movement during humoral responses.
T. Yi
,
Xiaoming Wang
,
+6 authors
J. Cyster
Immunity
2012
Corpus ID: 26198186
2010
2010
Effects of CYP7B1-mediated catalysis on estrogen receptor activation.
H. Pettersson
,
J. Lundqvist
,
M. Norlin
Biochimica et Biophysica Acta
2010
Corpus ID: 37008608
2009
2009
CYP7B1-mediated metabolism of 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol): a novel pathway for potential regulation of the cellular levels of androgens and neurosteroids.
H. Pettersson
,
J. Lundqvist
,
E. Oliw
,
M. Norlin
Biochimica et Biophysica Acta
2009
Corpus ID: 28446941
Highly Cited
2008
Highly Cited
2008
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
S. Biddinger
,
Joel T. Haas
,
+6 authors
C. Kahn
Nature Network Boston
2008
Corpus ID: 7684245
Despite the well-documented association between gallstones and the metabolic syndrome, the mechanistic links between these two…
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2008
2008
Hepatic insulin resistance ties cholesterol gallstone formation and the metabolic syndrome.
P. Kovacs
,
Ulrike Kurtz
,
H. Wittenburg
Annals of Hepatology
2008
Corpus ID: 2314502
2006
2006
Regulation of steroid hydroxylase CYP7B1 by androgens and estrogens in prostate cancer LNCaP cells.
Wanjin Tang
,
M. Norlin
Biochemical and Biophysical Research…
2006
Corpus ID: 34108716
2006
2006
Inter-conversion of 7alpha- and 7beta-hydroxy-dehydroepiandrosterone by the human 11beta-hydroxysteroid dehydrogenase type 1.
C. Muller
,
D. Pompon
,
P. Urban
,
R. Morfin
Journal of Steroid Biochemistry and Molecular…
2006
Corpus ID: 21094170
The dehydroepiandrosterone (DHEA) 7alpha-hydroxylation in humans takes place in the liver, skin, and brain. These organs are…
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2003
2003
Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in the rat.
S. Ren
,
Dalila Marques
,
+4 authors
W. Pandak
Metabolism: Clinical and Experimental
2003
Corpus ID: 21096107
Cholesterol metabolized to 7alpha-hydroxylated bile acids is a principle pathway of cholesterol degradation. Cholesterol 7alpha…
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2002
2002
Expression of key enzymes in bile acid biosynthesis during development: CYP7B1-mediated activities show tissue-specific differences.
M. Norlin
Journal of Lipid Research
2002
Corpus ID: 3123376
The developmental variation of cytochrome P450 (CYP)7A1, CYP7B1, CYP27A1, and 3beta-hydroxy-Delta(5)-C(27)-steroid dehydrogenase…
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