25-hydroxycholesterol 7alpha-hydroxylase activity

Known as: cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, CYP7B1 oxysterol 7alpha-hydroxylase activity, CYP7B1 
Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2017
01220022017

Papers overview

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2014
2014
11β-hydroxysteroid dehydrogenase type 1 (11HSD1) is an enzyme that amplifies intracellular glucocorticoid concentration by the… (More)
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Highly Cited
2012
Highly Cited
2012
7α,25-dihydroxycholesterol (7α,25-OHC) is a ligand for the G protein-coupled receptor EBI2; however, the cellular sources of this… (More)
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2009
2009
The current study presents data indicating that 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol) undergoes a previously… (More)
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Highly Cited
2008
Highly Cited
2008
Despite the well-documented association between gallstones and the metabolic syndrome, the mechanistic links between these two… (More)
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2008
2008
Despite the well-documented association between gallstones and the metabolic syndrome,1,2 the mechanistic links between these two… (More)
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2006
2006
The dehydroepiandrosterone (DHEA) 7alpha-hydroxylation in humans takes place in the liver, skin, and brain. These organs are… (More)
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2006
2006
The present study reports effects of androgens and estrogens on human CYP7B1 transcription in prostate cancer LNCaP cells… (More)
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2004
2004
Infection and inflammation induce the acutephase response (APR), leading to multiple alterations in lipid and lipoprotein… (More)
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2003
2003
Cholesterol metabolized to 7alpha-hydroxylated bile acids is a principle pathway of cholesterol degradation. Cholesterol 7alpha… (More)
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2002
2002
The developmental variation of cytochrome P450 (CYP)7A1, CYP7B1, CYP27A1, and 3beta-hydroxy-Delta(5)-C(27)-steroid dehydrogenase… (More)
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