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25-hydroxycholesterol 7alpha-hydroxylase activity

Known as: cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, CYP7B1 oxysterol 7alpha-hydroxylase activity, CYP7B1 
Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene… 
National Institutes of Health

Papers overview

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2017
2017
Background: Oxysterols are bioactive lipids that control cellular cholesterol synthesis, uptake, and exportation besides… 
Highly Cited
2008
Highly Cited
2008
Despite the well-documented association between gallstones and the metabolic syndrome, the mechanistic links between these two… 
2006
2006
The dehydroepiandrosterone (DHEA) 7alpha-hydroxylation in humans takes place in the liver, skin, and brain. These organs are… 
2003
2003
Cholesterol metabolized to 7alpha-hydroxylated bile acids is a principle pathway of cholesterol degradation. Cholesterol 7alpha… 
2002
2002
  • M. Norlin
  • Journal of lipid research
  • 2002
  • Corpus ID: 3123376
The developmental variation of cytochrome P450 (CYP)7A1, CYP7B1, CYP27A1, and 3beta-hydroxy-Delta(5)-C(27)-steroid dehydrogenase…