Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

25-hydroxycholesterol 7alpha-hydroxylase activity

Known as: cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity, CYP7B1 oxysterol 7alpha-hydroxylase activity, CYP7B1 
Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
7α,25-dihydroxycholesterol (7α,25-OHC) is a ligand for the G protein-coupled receptor EBI2; however, the cellular sources of this… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
Most of the many biological effects of estrogens are mediated via the estrogen receptors ERalpha and beta. The current study… Expand
Is this relevant?
2009
2009
The current study presents data indicating that 5alpha-androstane-3alpha,17beta-diol (3alpha-Adiol) undergoes a previously… Expand
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Despite the well-documented association between gallstones and the metabolic syndrome, the mechanistic links between these two… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
AbstractBiddinger SB, Haas JT, Yu BB, Bezy O, Jing E, ZhangW, Unterman TG, Carey MC, Kahn CR. Hepatic insu-lin resistance… Expand
Is this relevant?
2006
2006
The present study reports effects of androgens and estrogens on human CYP7B1 transcription in prostate cancer LNCaP cells… Expand
Is this relevant?
2006
2006
The dehydroepiandrosterone (DHEA) 7alpha-hydroxylation in humans takes place in the liver, skin, and brain. These organs are… Expand
Is this relevant?
2004
2004
Infection and inflammation induce the acutephase response (APR), leading to multiple alterations in lipid and lipoprotein… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2003
2003
Cholesterol metabolized to 7alpha-hydroxylated bile acids is a principle pathway of cholesterol degradation. Cholesterol 7alpha… Expand
Is this relevant?
2002
2002
The developmental variation of cytochrome P450 (CYP)7A1, CYP7B1, CYP27A1, and 3beta-hydroxy-Delta(5)-C(27)-steroid dehydrogenase… Expand
Is this relevant?