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21-deacetyldeflazacort

Known as: 21-hydroxy-deflazacort, 21-hydroxydeflazacort, 21-desacetyl-deflazacort 
 
National Institutes of Health

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L 6485

Papers overview

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2017
2017
Dual Therapy Deflazacort/Doxycyclyne Is Better Than Deflazacort Monotherapy to Alleviate Cardiomyopathy in Dystrophin-Deficient mdx Mice
Cardiomyopathy related to the absence of dystrophin is an important feature in Duchenne muscular dystrophy (DMD) and in the mdx… Expand
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2014
2014
[Pharmacokinetics of deflazacort tablets in healthy Chinese volunteers].
Deflazacort (DFZ, a prodrug) is well absorbed and rapidly metabolized into the active metabolite 21-hydroxydeflazacort (21-OH DFZ… Expand
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2013
2013
EPA protects against muscle damage in the mdx mouse model of Duchenne muscular dystrophy by promoting a shift from the M1 to M2 macrophage phenotype
In dystrophic mdx mice and in Duchenne muscular dystrophy, inflammation contributes to myonecrosis. Previously, we demonstrated… Expand
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2000
2000
Determination of 21-hydroxydeflazacort in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Application to bioequivalence study…
A liquid chromatographic atmospheric pressure chemical ionization tandem mass spectrometric method is described for the… Expand
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1995
1995
Expression and secretion of parathyroid hormone‐related protein by human bone‐derived cells in vitro: Effects of glucocorticoids
We investigated the production of parathyroid hormone‐related protein (PTHrP) by cells derived from explants of human bone. Using… Expand
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1994
1994
Extraction and high-performance liquid chromatographic separation of deflazacort and its metabolite 21-hydroxydeflazacort. Application to urine samples.
Two HPLC methods for the separation of a mixture of corticoids including the oxazolinic corticoid deflazacort and its metabolite… Expand
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