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20-carboxyleukotriene B4
Known as:
6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))-
, 20-COOH LTB4
, 20-carboxy-leukotriene B4
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Hydroxyeicosatetraenoic Acids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1997
Highly Cited
1997
Effect of the lipidic lipidosterolic extract of Serenoa repens (Permixon) on the ionophore A23187-stimulated production of leukotriene B4 (LTB4) from human polymorphonuclear neutrophils.
M. Paubert-Braquet
,
J. M. Mencia Huerta
,
H. Cousse
,
P. Braquet
Prostaglandins, leukotrienes, and essential fatty…
1997
Corpus ID: 1218496
Although the lipidic extract of Serenoa repens (LESSr, Permixon, Sereprostat) is widely used in patients suffering from benign…
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1994
1994
Effect of Pygeum africanum extract on A23187-stimulated production of lipoxygenase metabolites from human polymorphonuclear cells.
M. Paubert-Braquet
,
A. Cavé
,
+4 authors
P. Borgeat
Journal of lipid mediators and cell signalling
1994
Corpus ID: 21600444
Pygeum africanum extract has been used for more than 20 years in France in patients suffering from benign prostatic hypertrophy…
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1990
1990
Oxidation of 20-hydroxyleukotriene B4 to 20-carboxyleukotriene B4 by human neutrophil microsomes. Role of aldehyde dehydrogenase and leukotriene B4 omega-hydroxylase (cytochrome P-450LTB omega) in…
H. Sumimoto
,
S. Minakami
The Journal of biological chemistry
1990
Corpus ID: 25460899
Leukotriene B4 (LTB4), a potent chemoattractant for leukocytes, is catabolized by human neutrophils via omega-oxidation…
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1989
1989
Human red cells enhance the formation of 5-lipoxygenase-derived products by neutrophils.
A. Stern
,
C. Serhan
Free radical research communications
1989
Corpus ID: 36237770
Upon activation, human neutrophils generate 5-lipoxygenase products which are involved in inflammation as well as other…
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Highly Cited
1988
Highly Cited
1988
Leukotriene production in human neutrophils primed by recombinant human granulocyte/macrophage colony-stimulating factor and stimulated with the complement component C5A and FMLP as second signals
C. Dahinden
,
J. Zingg
,
F. Maly
,
A. D. de Weck
The Journal of experimental medicine
1988
Corpus ID: 13110680
Neutrophils (PMN) preincubated with recombinant human granulocyte/macrophage colony-stimulating factor (rhGM-CSF) for 2 h and…
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1988
1988
A comparison of effects of sulfasalazine and its metabolites on the metabolism of endogenous vs. exogenous arachidonic acid.
H. Allgayer
,
W. Stenson
Immunopharmacology
1988
Corpus ID: 13679047
Sulfasalazine and, to a lesser extent, 5-aminosalicylic acid and N-acetyl-aminosalicylic acid, were found to block production of…
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1988
1988
Cytoplasmic pH change induced by leukotriene B4 in human neutrophils.
H. Sumimoto
,
M. Satoh
,
K. Takeshige
,
E. Cragoe
,
S. Minakami
Biochimica et biophysica acta
1988
Corpus ID: 24826371
Leukotriene B4 induced a biphasic change in the cytoplasmic pH of human neutrophils: an initial rapid acidification followed by…
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1988
1988
NAD+-dependent oxidation of 20-hydroxyleukotriene B4 to 20-carboxyleukotriene B4 by rat liver cytosol.
Y. Gotoh
,
H. Sumimoto
,
K. Takeshige
,
S. Minakami
Biochimica et biophysica acta
1988
Corpus ID: 22486780
20-Hydroxyleukotriene B4 was converted by rat liver homogenates in the presence of NAD+ to a more polar product on reverse-phase…
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1987
1987
Enhanced capacity for release of leucotriene B4 by neutrophils in rheumatoid arthritis.
J. Elmgreen
,
O. Nielsen
,
I. Ahnfelt-Rønne
Annals of the rheumatic diseases
1987
Corpus ID: 34008617
The calcium dependent metabolism of endogenous arachidonic acid (AA) was investigated in 17 patients with rheumatoid arthritis…
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1987
1987
A novel metabolic pathway for leukotriene B4 in different cell types: primary reduction of a double bond.
V. Kaever
,
M. Martín
,
J. Fauler
,
K. Marx
,
K. Resch
Biochimica et biophysica acta
1987
Corpus ID: 21770158
Addition of leukotriene B4 together with trace amounts of tritiated leukotriene B4 to different cell types, such as bone marrow…
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