Skip to search formSkip to main contentSkip to account menu

2-propyl-4-pentenoic acid

Known as: 4-en-VPA, 4-ene VPA, 4-ene valproic acid 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Metabolism and renal excretion of valproic acid (VPA) were examined in maternal, fetal, and newborn sheep to identify the… 
1997
1997
An earlier study in rats revealed that alpha-fluorination of 2-propyl-4-pentenoic acid (4-ene VPA), a toxic metabolite of the… 
Highly Cited
1995
Highly Cited
1995
It is postulated that the hepatotoxicity of valproic acid (VPA) results from the mitochondrial beta-oxidation of its cytochrome… 
1992
1992
Summary: To investigate the association between valproate metabolism (VPA) and VPA‐induced hyperammonemia together with the… 
Highly Cited
1991
Highly Cited
1991
The severe hepatotoxicity of valproic acid (VPA) is believed to be mediated through reactive metabolites. The formation of… 
Highly Cited
1990
Highly Cited
1990
The incidence of valproic acid hepatotoxicity has been reported to increase in patients who are receiving polytherapy. A minor…