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2-phenylacetylenesulfonamide

Known as: 2-phenylethynesulfonamide 
National Institutes of Health

Papers overview

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2016
2016
Photothermal treatment, a new approach for inactivation of bacteria and pathogens that does not depend on traditional therapeutic… Expand
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2014
2014
The effect of 2-phenylethynesulfonamide (PES), which is a p53 and HSP70 inhibitor in mammalian cells, was studied on the rainbow… Expand
Highly Cited
2013
Highly Cited
2013
The molecular chaperones of the Hsp70 family have been recognized as targets for anti-cancer therapy. Since several paralogs of… Expand
Highly Cited
2013
Highly Cited
2013
The stress-induced HSP70 is an ATP-dependent molecular chaperone that plays a key role in refolding misfolded proteins and… Expand
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Highly Cited
2013
Highly Cited
2013
Heat-shock protein (HSP) 70 is aberrantly expressed in different malignancies and has a cancer-specific cell-protective effect… Expand
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2013
2013
The endotoxin-mediated production of pro-inflammatory cytokines plays an important role in the pathogenesis of liver disorders… Expand
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Highly Cited
2011
Highly Cited
2011
The evolutionarily conserved stress-inducible HSP70 molecular chaperone plays a central role in maintaining protein quality… Expand
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2011
2011
The p14/p19ARF (ARF) tumor suppressor gene is frequently mutated in human cancer. Recently ARF has been shown to localize to… Expand
Highly Cited
2009
Highly Cited
2009
The multifunctional, stress-inducible molecular chaperone HSP70 has important roles in aiding protein folding and maintaining… Expand
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2009
2009
We studied the actions of 2-phenylacetylenesulfonamide (PAS) on B-chronic lymphocytic leukemia (CLL) cells. PAS (5-20 microM… Expand
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