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Photothermal treatment, a new approach for inactivation of bacteria and pathogens that does not depend on traditional therapeutic… Expand The effect of 2-phenylethynesulfonamide (PES), which is a p53 and HSP70 inhibitor in mammalian cells, was studied on the rainbow… Expand The molecular chaperones of the Hsp70 family have been recognized as targets for anti-cancer therapy. Since several paralogs of… Expand The stress-induced HSP70 is an ATP-dependent molecular chaperone that plays a key role in refolding misfolded proteins and… Expand Heat-shock protein (HSP) 70 is aberrantly expressed in different malignancies and has a cancer-specific cell-protective effect… Expand The endotoxin-mediated production of pro-inflammatory cytokines plays an important role in the pathogenesis of liver disorders… Expand The evolutionarily conserved stress-inducible HSP70 molecular chaperone plays a central role in maintaining protein quality… Expand The p14/p19ARF (ARF) tumor suppressor gene is frequently mutated in human cancer. Recently ARF has been shown to localize to… Expand The multifunctional, stress-inducible molecular chaperone HSP70 has important roles in aiding protein folding and maintaining… Expand We studied the actions of 2-phenylacetylenesulfonamide (PAS) on B-chronic lymphocytic leukemia (CLL) cells. PAS (5-20 microM… Expand