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2-oxoglutarate metabolic process

Known as: 2-oxoglutarate metabolism, 2-ketoglutarate metabolic process, alpha-ketoglutarate metabolic process 
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key… 
National Institutes of Health

Papers overview

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2012
2012
Synthesis of the 1-monoester of 2-ketoalkanedioic acids, for example, octyl α-ketoglutarate.
Oxidative cleavage of cycloalkene-1-carboxylates, made from the corresponding carboxylic acids, and subsequent oxidation of the… 
Review
2008
Review
2008
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection.
Most homeostatic processes including gene transcription occur as a result of deviations in physiological tone that threatens the… 
2006
2006
Regulation of 2-oxoglutarate metabolism in rat liver by NADP-isocitrate dehydrogenase and aspartate aminotransferase
Kinetic and regulatory properties of NADP-isocitrate dehydrogenase (NADP-IDH) and aspartate aminotransferase (AsAT) responsible… 
2002
2002
Plasma Lysine Concentration and Availability of 2-Ketoglutarate in Liver Mitochondria
Defects of lysine metabolism are rare, but hyperlysinemia is a concomitant of many inborn errors of metabolism, including urea… 
Highly Cited
1997
Highly Cited
1997
Ornithine alpha-ketoglutarate metabolism after enteral administration in burn patients: bolus compared with continuous infusion.
Ornithine alpha-ketoglutarate (OKG) has been successfully used as an enteral supplement in the treatment of catabolic states… 
Review
1978
Review
1978
Ammonia metabolism.
The pathways responsible for an the mechanisms underlying the adaptive increase in ammonia production in response to acidosis are… 
1978
1978
Glucagon‐induced stimulation of 2‐oxoglutarate metabolism in mitochondria from rat liver
Highly Cited
1977
Highly Cited
1977
Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria.
1. The apparent Michaelis constants of the glutamate dehydrogenase (EC 1.4.1.3), the glutamate-oxaloacetate transaminase (EC 2.6… 
1974
1974
EFFECT OF THIAMINE DEPRIVATION AND THIAMINE ANTAGONISTS ON THE LEVEL OF γ‐AMINOBUTYRIC ACID AND ON 2‐OXOGLUTARATE METABOLISM IN RAT BRAIN 1 2
Brain levels of y‐aminobutyric acid (GABA), glutamate and 2‐oxoglutarate, activities of glutamate decarboxylase GABA‐transaminase… 
1974
1974
Regulation of mitochondrial alpha-ketoglutarate metabolism by product inhibition at alpha-ketoglutarate dehydrogenase.
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