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2-keto-4-pentenoic acid

Known as: 2-oxopentenoic acid 
 
National Institutes of Health

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1 relation

Broader (1)

Fatty Acids, Monounsaturated

Papers overview

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1988
1988
Injection of L-allylglycine into the posterior hypothalamus in rats causes decreases in local gaba which correlate with increases in heart rate
Injection of the GABA antagonist, bicuculline methiodide into the posterior hypothalamus of rats has been shown to cause marked… Expand
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1981
1981
Metabolism of allylglycine and cis-crotylglycine by Pseudomonas putida (arvilla) mt-2 harboring a TOL plasmid.
Spontaneous mutants which acquired the ability to utilize d-allylglycine (d-2-amino-4-pentenoic acid) and dl-cis-crotylglycine… Expand
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1979
1979
INHIBITION OF BRAIN GLUTAMATE DECARBOXYLASE BY 2‐KETO‐4‐PENTENOIC ACID, A METABOLITE OF ALLYLGLYCINE 1
Abstract— 2‐Keto‐4‐pentenoic acid, a potent inhibitor of brain glutamate decarboxylase (Orlowskiet al., 1977) was prepared by… Expand
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1978
1978
The role of 2-keto-4-pentenoic acid in seizures induced by allylglycine.
  • R. Horton
  • Biochemical pharmacology
  • 1978
    • Corpus ID: 32401386
Abstract 2 Keto-4-pentenoic acid (2K4PA) was synthesised from l -allylglycine (L-AG) using purified l -amino acid oxidase and… Expand
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Highly Cited
1978
Highly Cited
1978
REGIONAL CHANGES IN CEREBRAL GABA CONCENTRATION AND CONVULSIONS PRODUCED BY d AND BY l‐ALLYLGLYCINE
Abstract— The convulsant action of allylglycine (2‐amino‐4‐pentenoic acid) is due to the metabolic conversion of allylglycine to… Expand
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1978
1978
Behavioural effects of allylglycine (2-amino-4-pentenoic acid) and 2-keto-4-pentenoic acid following focal injection into the rat cerebellum and caudate nucleus [proceedings].
 
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Highly Cited
1977
Highly Cited
1977
D‐ AND L‐STEREOISOMERS OF ALLYLGLYCINE: CONVULSIVE ACTION AND INHIBITION OF BRAIN L‐GLUTAMATE DECARBOXYLASE
DL‐Allylglycine was resolved into the L‐ and D‐stereoisomers using hog kidney acylase. Both isomers were active as convulsants… Expand
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1977
1977
A comparison of the effects of allylglycine and 2-keto-4-pentenoic acid on cerebral glutamic acid decarboxylase activity and convulsions in mice [proceedings].
 
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