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2-isopropyl-6-methyl-4-pyrimidinol

 
National Institutes of Health

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Pyrimidines

Papers overview

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2016
2016
Increased diazinon hydrolysis to 2-isopropyl-6-methyl-4-pyrimidinol in liquid medium by a specific Streptomyces mixed culture.
Actinobacteria identified as Streptomyces spp. were evaluated for their ability to remove diazinon as the only carbon source from… Expand
2015
2015
In vitro evaluation of neurotoxicity potential and oxidative stress responses of diazinon and its degradation products in rat brain synaptosomes.
Although primary toxic action of organophosphorous insecticides is associated with acetylcholinesterase inhibition, later studies… Expand
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2011
2011
Toxicokinetic model describing bioconcentration and biotransformation of diazinon in Daphnia magna.
A toxicokinetic model for Daphnia magna , which simulates the internal concentration of the insecticide diazinon, its… Expand
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2011
2011
Sublethal genotoxicity and cell alterations by organophosphorus pesticides in MCF-7 cells: implications for environmentally relevant concentrations.
Organophosphorus pesticide (OPP) toxicity is believed to be mediated through inhibition of acetylcholinesterase (AChE). Given… Expand
Highly Cited
2010
Highly Cited
2010
Toxic effects of diazinon and its photodegradation products.
The toxic effects of diazinon and its irradiated solutions were investigated using cultivated human blood cells (lymphocytes and… Expand
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Highly Cited
2010
Highly Cited
2010
Toxicokinetic and toxicodynamic modeling explains carry-over toxicity from exposure to diazinon by slow organism recovery.
Carry-over toxicity occurs when organisms exposed to an environmental toxicant survive but carry some damage resulting in reduced… Expand
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2010
2010
Exposures of preschool children to chlorpyrifos, diazinon, pentachlorophenol, and 2,4-dichlorophenoxyacetic acid over 3 years from 2003 to 2005: A longitudinal model
The impact of the US EPA-required phase-outs starting in 2000–2001 of residential uses of the organophosphate (OP) pesticides… Expand
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2006
2006
Highly selective sample preparation and gas chromatographic-mass spectrometric analysis of chlorpyrifos, diazinon and their major metabolites in sludge and sludge-fertilized agricultural soils.
A pressurized liquid extraction (PLE) solid-phase extraction (SPE) gas chromatography-mass spectrometry (GC-MS) method was… Expand
Highly Cited
2003
Highly Cited
2003
Investigations of the determination and transformations of diazinon and malathion under environmental conditions using gas chromatography coupled with a flame ionisation detector.
Degradation of two model insecticides, diazinon and malathion, and their degradation products 2-isopropyl-6-methyl-4-pyrimidinol… Expand
2001
2001
Determination of diazinon, chlorpyrifos, and their metabolites in rat plasma and urine by high-performance liquid chromatography.
This study reports a simple and rapid high-performance liquid chromatographic (HPLC) method for the determination of the… Expand
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