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2-hydroxysaclofen

Known as: Benzeneethanesulfonic acid, beta-(aminomethyl)-4-chloro-beta-hydroxy-, 3-amino-2-(4-chlorophenyl)-2-hydroxypropylsulfonic acid, 2-OH-saclofen 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

BaclofenGABA-B Receptor Antagonists
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Activaton of gabab receptor inhibits the excitability of rat small diameter trigeminal root ganglion neurons
A selective GABA(B) receptor agonist, baclofen, is known to suppress neuropathic pain. In the present study, we investigated the… 
Highly Cited
1998
Highly Cited
1998
Blockade and Recovery of Spontaneous Rhythmic Activity after Application of Neurotransmitter Antagonists to Spinal Networks of the Chick Embryo
We studied the regulation of spontaneous activity in the embryonic (day 10–11) chick spinal cord. After bath application ofeither… 
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Highly Cited
1996
Highly Cited
1996
Differential regulation of 5‐hydroxytryptamine release by GABAA and GABAB receptors in midbrain raphe nuclei and forebrain of rats
1 Extracellular 5‐hydroxytryptamine (5‐HT) was determined in dorsal raphe nucleus (DRN), median raphe nucleus (MRN) and nucleus… 
Highly Cited
1995
Highly Cited
1995
GABAA receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons
Evidence from electrophysiological studies has suggested an inhibitory interaction between GABAergic neurons in substantia nigra… 
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Highly Cited
1994
Highly Cited
1994
gamma-Aminobutyric acid is an inhibitory neurotransmitter restricting the release of luteinizing hormone-releasing hormone before the onset of puberty.
To test the hypothesis that the pubertal increase in luteinizing hormone-releasing hormone (LHRH) release is withheld by a… 
Highly Cited
1993
Highly Cited
1993
Pharmacology of GABA receptor CI− channels in rat retinal bipolar cells
γ-AMlNOBUTYRlC acid (GABA), a major inhibitory neurotransmitter in the mammalian nervous system, is known to operate bicuculline… 
Highly Cited
1993
Highly Cited
1993
Actions of 5-hydroxytryptamine on neurons of the rat cingulate cortex.
1. Intracellular recordings were made from layer V pyramidal neurons in slices of rat cingulate cortex. Electrodes contained… 
Highly Cited
1993
Highly Cited
1993
A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord
1 Neuropharmacological actions of a novel metabotropic glutamate receptor agonist, (2S,1′R,2′R,3′R)‐2‐(2,3‐dicarboxycyclopropyl… 
Highly Cited
1992
Highly Cited
1992
Two types of neurone in the rat ventral tegmental area and their synaptic inputs.
1. Intracellular recordings were made from 241 ventral tegmental neurones in slices of rat midbrain. Seventy‐seven per cent of… 
Highly Cited
1992
Highly Cited
1992
5-hydroxytryptamine1B receptors block the GABAB synaptic potential in rat dopamine neurons
Intracellular recordings were made from presumed dopamine-containing neurons in slices cut from the midbrain of the rat. Focal… 
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