2-hydroxysaclofen

Known as: Benzeneethanesulfonic acid, beta-(aminomethyl)-4-chloro-beta-hydroxy-, 3-amino-2-(4-chlorophenyl)-2-hydroxypropylsulfonic acid, 2-OH-saclofen 
 
National Institutes of Health

Papers overview

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2004
2004
A selective GABA(B) receptor agonist, baclofen, is known to suppress neuropathic pain. In the present study, we investigated the… (More)
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2004
2004
CA1 pyramidal cells receive two major excitatory inputs: the perforant path (PP) terminates in the most distal dendrites, whereas… (More)
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Highly Cited
1999
Highly Cited
1999
An emerging hypothesis to explain the mechanism of heroin-induced positive reinforcement states that opiates inhibit gamma… (More)
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Highly Cited
1998
Highly Cited
1998
We studied the regulation of spontaneous activity in the embryonic (day 10-11) chick spinal cord. After bath application of… (More)
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Highly Cited
1995
Highly Cited
1995
Evidence from electrophysiological studies has suggested an inhibitory interaction between GABAergic neurons in substantia nigra… (More)
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Highly Cited
1994
Highly Cited
1994
To test the hypothesis that the pubertal increase in luteinizing hormone-releasing hormone (LHRH) release is withheld by a… (More)
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Highly Cited
1993
Highly Cited
1993
γ-AMlNOBUTYRlC acid (GABA), a major inhibitory neurotransmitter in the mammalian nervous system, is known to operate bicuculline… (More)
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Highly Cited
1993
Highly Cited
1993
1. Intracellular recordings were made from layer V pyramidal neurons in slices of rat cingulate cortex. Electrodes contained… (More)
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Highly Cited
1992
Highly Cited
1992
1. Intracellular recordings were made from 241 ventral tegmental neurones in slices of rat midbrain. Seventy-seven per cent of… (More)
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Highly Cited
1992
Highly Cited
1992
Intracellular recordings were made from presumed dopamine-containing neurons in slices cut from the midbrain of the rat. Focal… (More)
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