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2-hydroxyatorvastatin
Known as:
2-hydroxy-atorvastatin
, ortho-hydroxyatorvastatin
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Atorvastatin calcium
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Development, validation and application of a novel HPLC-MS/MS method for the quantification of atorvastatin, bisoprolol and clopidogrel in a large cardiovascular patient cohort
R. Turner
,
V. Fontana
,
M. Bayliss
,
S. Whalley
,
Anahi Santoyo Castelazo
,
M. Pirmohamed
Journal of Pharmaceutical and Biomedical Analysis
2018
Corpus ID: 51624969
2017
2017
High-Dose Metformin May Increase the Concentration of Atorvastatin in the Liver by Inhibition of Multidrug Resistance-Associated Protein 2.
E. Shin
,
Naree Shin
,
Ju‐Hee Oh
,
Young-Joo Lee
Journal of Pharmacy and Science
2017
Corpus ID: 4638168
2017
2017
The effect of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Chinese people.
Yaqin Wang
,
Ying-ying Tian
,
+8 authors
D. Ouyang
Pharmazie
2017
Corpus ID: 46768967
The pharmacokinetics of statins show substantial inter-subject variability. Increasing systemic exposure of statins may lead to…
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2014
2014
The effect of CYP3A4*1G allele on the pharmacokinetics of atorvastatin in Chinese han patients with coronary heart disease
B. He
,
Lei Shi
,
J. Qiu
,
Xiaohui Zeng
,
Shujin Zhao
Journal of clinical pharmacology
2014
Corpus ID: 36328557
The present study aimed to evaluate the impact of CYP3A4*1G allele on the pharmacokinetics of atorvastatin in the Chinese Han…
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Highly Cited
2011
Highly Cited
2011
Effect of Gemfibrozil and Fenofibrate on the Pharmacokinetics of Atorvastatin
L. Whitfield
,
A. Porcari
,
C. Alvey
,
R. Abel
,
W. Bullen
,
D. Hartman
Journal of clinical pharmacology
2011
Corpus ID: 21374199
Coadministration of statins and fibrates is beneficial in some patients by allowing simultaneous reduction of triglycerides and…
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2010
2010
Effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Korean subjects.
Y. J. Lee
,
M. Lee
,
L. A. Lim
,
S. Jang
,
J. Chung
International journal of clinical pharmacology…
2010
Corpus ID: 40531657
OBJECTIVE This study aimed to evaluate the effect of genetic polymorphisms of SLCO1B1 and ABCB1 on the pharmacokinetics of…
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2008
2008
Effect of omega-3-acid ethyl esters on steady-state plasma pharmacokinetics of atorvastatin in healthy adults.
M. Di Spirito
,
G. Morelli
,
R. Doyle
,
J. Johnson
,
J. Mckenney
Expert Opinion on Pharmacotherapy
2008
Corpus ID: 42106960
BACKGROUND Prescription omega-3-acid ethyl esters (P-OM3) have been used as adjunctive therapy to statin drugs in patients with…
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Highly Cited
2007
Highly Cited
2007
Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin
M. Pasanen
,
H. Fredrikson
,
P. Neuvonen
,
M. Niemi
Clinical pharmacology and therapy
2007
Corpus ID: 1015828
Thirty‐two healthy volunteers with different SLCO1B1 genotypes ingested a 20 mg dose of atorvastatin and 10 mg dose of…
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Highly Cited
2006
Highly Cited
2006
Validated HPLC–MS–MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma—pharmacokinetic study
V. Bořek-Dohalský
,
J. Huclová
,
B. Barrett
,
B. Němec
,
I. Ulč
,
I. Jelínek
Analytical and Bioanalytical Chemistry
2006
Corpus ID: 39072888
Cholesterol-reducing statin drugs are the most frequently prescribed agents for reducing morbidity and mortality related to…
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Highly Cited
1999
Highly Cited
1999
Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry.
M. Jemal
,
Z. Ouyang
,
B. Chen
,
D. Teitz
Rapid Communications in Mass Spectrometry
1999
Corpus ID: 36504118
A method for simultaneous quantitation of both the acid and lactone forms of atorvastatin, a new synthetic inhibitor of HMG-CoA…
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