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2-hydroxyatorvastatin

Known as: 2-hydroxy-atorvastatin, ortho-hydroxyatorvastatin 
 
National Institutes of Health

Papers overview

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2018
2018
HighlightsCardiovascular disease is a leading cause of morbidity and mortality.There is notable interindividual variation in… Expand
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2017
2017
The pharmacokinetics of statins show substantial inter-subject variability. Increasing systemic exposure of statins may lead to… Expand
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2014
2014
The present study aimed to evaluate the impact of CYP3A4*1G allele on the pharmacokinetics of atorvastatin in the Chinese Han… Expand
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2011
2011
Coadministration of statins and fibrates is beneficial in some patients by allowing simultaneous reduction of triglycerides and… Expand
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2010
2010
OBJECTIVE This study aimed to evaluate the effect of genetic polymorphisms of SLCO1B1 and ABCB1 on the pharmacokinetics of… Expand
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2010
2010
The aim of the present study was to develop a chromatographic method for the analysis of atorvastatin, Ortho- and Para… Expand
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2008
2008
BACKGROUND Prescription omega-3-acid ethyl esters (P-OM3) have been used as adjunctive therapy to statin drugs in patients with… Expand
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Highly Cited
2007
Highly Cited
2007
Thirty‐two healthy volunteers with different SLCO1B1 genotypes ingested a 20 mg dose of atorvastatin and 10 mg dose of… Expand
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Highly Cited
2006
Highly Cited
2006
Cholesterol-reducing statin drugs are the most frequently prescribed agents for reducing morbidity and mortality related to… Expand
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Highly Cited
1999
Highly Cited
1999
A method for simultaneous quantitation of both the acid and lactone forms of atorvastatin, a new synthetic inhibitor of HMG-CoA… Expand
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