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2-hexynyladenosine-5'-N-ethylcarboxamide

Known as: 2-hexynyl-5'-N-ethylcarboxamidoadenosine, 2-hexynyl-NECA, HENECA 
National Institutes of Health

Papers overview

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2014
2014
Alzheimer's disease (AD) is the leading cause of senile dementia in today's society. Its debilitating symptoms are manifested by… Expand
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2004
2004
SummaryIntracellular recordings were performed in α1-pontine slice preparation of the rat brain containing the locus coeruleus… Expand
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Review
2003
Review
2003
The search for potent and selective A(2A) adenosine receptor agonists has been particularly fruitful in the early nineties. A… Expand
2002
2002
Although molecular biology studies indicate the presence of adenosine A(2A) receptors in the rat hippocampus, the pharmacological… Expand
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Highly Cited
2000
Highly Cited
2000
The hippocampal GABAergic system is assumed not to be a target for purine modulation. We have now confirmed that neither… Expand
Highly Cited
1997
Highly Cited
1997
1 In the present study, we investigated the ability of a recently introduced non‐xanthine A2A receptor antagonist, ZM241385 (4‐(2… Expand
Highly Cited
1997
Highly Cited
1997
Expression of the early-gene c-fos is an useful method for studying potential sites of action of drugs active in the CNS… Expand
1995
1995
A series of new 2-aralkynyl and 2-heteroaralkynyl derivatives of NECA were synthesized and studied in binding and functional… Expand
Highly Cited
1984
Highly Cited
1984
The effects of N6-L-(phenylisopropyl)adenosine, cyclohexyladenosine and adenosine-5'-N-ethylcarboxamide on sleep were examined in… Expand
1984
1984
Various adenosine derivatives, methylxanthines and other compounds were tested for their abilities to inhibit the rapid uptake of… Expand