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2-ethoxyestradiol

Known as: 1,3,5(5)-estratrien-2,3,17-triol 2-ethyl ether 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Estradiol
analogs & derivatives

Papers overview

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Highly Cited
2008
Highly Cited
2008
2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling.
2007
2007
2-Methoxyestradiol and 2-Ethoxyestradiol Retard the Progression of Renal Disease in Aged, Obese, Diabetic ZSF1 Rats
The metabolic syndrome is a main cause for cardiovascular disease and for the accelerating epidemic of chronic renal failure… 
Highly Cited
2000
Highly Cited
2000
A steroid derivative with paclitaxel-like effects on tubulin polymerization.
The endogenous estrogen metabolite 2-methoxyestradiol has modest antimitotic activity that may result from a weak interaction at… 
Highly Cited
2000
Highly Cited
2000
Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
2-Methoxyestradiol is a cytotoxic human metabolite of estradiol with the ability to bind to the colchicine site of tubulin and… 
Highly Cited
1995
Highly Cited
1995
Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to…
In order to define the structural parameters associated with the antitubulin activity and cytotoxicity of 2-methoxyestradiol, a… 
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