FAQ

2-deoxy-D-gluconate 3-dehydrogenase activity

Known as: 2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity, 2-deoxygluconate dehydrogenase activity, 2-keto-3-deoxygluconate oxidoreductase activity 
Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+. [EC:1.1.1.125]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2012
0119772012

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative.
The 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative, designated Cf2891, was found to inhibit a variety of… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures.
Endothelial progenitor cell (EPC) cultures and colony-forming units (CFUs) have been extensively studied for their therapeutic… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2006
2006
Neurogenic insulin resistance in guinea-pigs with cisplatin-induced neuropathy.
The aim of the present work was to study whether neurotoxicity produced by cisplatin modified tissue insulin sensitivity in… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Optimizing Cancer Radiotherapy with 2-Deoxy-D-Glucose
Higher rates of glucose utilization and glycolysis generally correlate with poor prognosis in several types of malignant tumors… (More)
  • table 1
Is this relevant?
2003
2003
Thymidine phosphorylase induces angiogenesis in vivo and in vitro: an evaluation of possible mechanisms.
1 Thymidine phosphorylase (TP) is elevated in the plasma of cancer patients, and has been implicated in pathophysiological… (More)
Is this relevant?
1993
1993
Transport of D-fructose and its analogues by Trypanosoma brucei.
Kinetic parameters for entry of D-fructose into Trypanosoma brucei brucei have been determined. The net uptake of D-fructose was… (More)
Is this relevant?
1980
1980
Effect of glucoprivation induced by 2-deoxy-D-glucose on serum gonadotropin levels, pituitary response to GnRH and progesterone-induced release of luteinizing hormone in rats.
Intact (experiment 1) or castrated (experiment 2) male rats were either fed or fasted for 24 hours. Half of each group received… (More)
Is this relevant?
1977
1977
Evidence for antral inhibition of pentagastrin from experiments using mucosal cooling.
1. The acid secretion of the fundic mucosa in Heidenhain pouches in response to pentagastrin became progressively less as the… (More)
Is this relevant?