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2-dehydro-3-deoxy-phosphogluconate aldolase activity

Known as: KDPG aldolase activity, 2-keto-3-deoxy-6-phosphogluconate aldolase activity, phospho-2-dehydro-3-deoxygluconate aldolase activity 
Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate. [EC:4.1.2.14]
National Institutes of Health

Papers overview

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2018
2018
Bioinformatic analysis of the fold type I PLP‐dependent enzymes reveals determinants of reaction specificity in l‐threonine aldolase from Aeromonas jandaei
Understanding the role of specific amino acid residues in the molecular mechanism of a protein's function is one of the most… 
2009
2009
Cloning, expression, and characterization of a new deoxyribose 5-phosphate aldolase from Yersinia sp. EA015.
2008
2008
Gene Cloning of α-Methylserine Aldolase from Variovorax paradoxus and Purification and Characterization of the Recombinant Enzyme
The α-methylserine aldolase gene from Variovorax paradoxus strains AJ110406, NBRC15149, and NBRC15150 was cloned and expressed in… 
2005
2005
The occurrence of the Entner-Doudoroff pathway in bacteria
The occurrence of the two key enzymes of the Entner-Doudoroff pathway, gluconate-6-phosphate dehydrase and 2-keto-3… 
2004
2004
Isolation and transcriptional regulation of the Kluyveromyces lactis FBA1 (fructose-1,6-bisphosphate aldolase) gene.
Cloning and transcriptional regulation of the KlFBA1 gene that codes for the class II fructose-1,6-bisphosphate aldolase of the… 
Highly Cited
1994
Highly Cited
1994
Genetic analysis of the O-specific lipopolysaccharide biosynthesis region (rfb) of Escherichia coli K-12 W3110: identification of genes that confer group 6 specificity to Shigella flexneri serotypes…
We recently reported a novel genetic locus located in the sbcB-his region of the chromosomal map of Escherichia coli K-12 which… 
1994
1994
Purification and characterization of 2-keto-3-deoxy-6-phosphogluconate aldolase from Azotobacter vinelandii: evidence that the enzyme is bifunctional towards 2-keto-4-hydroxy glutarate cleavage.
2-keto-3-deoxy-6-phosphogluconate aldolase (E.C. 4.1.2.14) has been purified in two chromatographic steps to 99% purity in 73… 
Highly Cited
1985
Highly Cited
1985
Treponema saccharophilum sp. nov., a large pectinolytic spirochete from the bovine rumen
A large, obligately anaerobic spirochete (strain PB) was isolated from bovine rumen fluid by a procedure involving rifampin as a… 
1973
1973
Utilization of gluconate by Escherichia coli. Induction of gluconate kinase and 6-phosphogluconate dehydratase activities.
1. A mutant of Escherichia coli, devoid of phosphopyruvate synthetase, glucosephosphate isomerase and 6-phosphogluconate… 
Highly Cited
1968
Highly Cited
1968
Selection of Escherichia coli Mutants Lacking Glucose-6-Phosphate Dehydrogenase or Gluconate-6-Phosphate Dehydrogenase
  • D. Fraenkel
  • Journal of bacteriology
  • 1968
  • Corpus ID: 46426218
Glucose is metabolized in Escherichia coli chiefly via the phosphoglucose isomerase reaction; mutants lacking that enzyme grow… 
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