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Quicker onset and shorter elimination time favours (+/-) articaine as a short-acting local anaesthetic for regional anaesthesia… Expand The aim of the investigation was to assess the pharmacokinetic characteristics and safety of articaine HCl used in tumescent… Expand BACKGROUND AND OBJECTIVES
With increasing age, there are physiologic changes that could affect pharmacokinetics of drugs. More… Expand A new method is described using solid-phase extraction (SPE) for preconcentration of articaine and the metabolite articainic acid… Expand SummaryArticaine is the most widely used local anaesthetic agent in dentistry in a number of European countries. The amide… Expand AIMS
To study the pharmacokinetics of articaine and its metabolite articainic acid, in patients undergoing intravenous regional… Expand Background and Objectives The amide-type local anesthetic articaine is unique in that hydrolysis to articainic acid by serum… Expand This study was undertaken to develop a time- and cost-effective method for the detection of articaine and articainic acid in… Expand Articaine is metabolized into articainic acid. The half-lives of articaine are 0.54 +/- 0.05 and 2.44 +/- 0.30 h and that of its… Expand