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2-carboxyarticaine

Known as: articainic acid 
National Institutes of Health

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Articaine
analogs & derivatives

Papers overview

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Review
2005
Review
2005
Clinical pharmacology and the use of articaine for local and regional anaesthesia.
2004
2004
Pharmacokinetics of Articaine Hydrochloride in Tumescent Local Anesthesia for Liposuction
The aim of the investigation was to assess the pharmacokinetic characteristics and safety of articaine HCl used in tumescent… 
1999
1999
The effect of age on pharmacokinetics of the local anesthetic drug articaine.
1999
1999
Solid-phase extraction and high-performance liquid chromatographic determination of articainic and its metabolite articainic acid in human serum.
  • K. Richter, R. Oertel
  • Journal of chromatography. B, Biomedical sciences…
  • 1999
  • Corpus ID: 33580229
Review
1997
Review
1997
Clinical Pharmacokinetics of Articaine
SummaryArticaine is the most widely used local anaesthetic agent in dentistry in a number of European countries. The amide… 
1997
1997
Regional metabolism of articaine in 10 patients undergoing intravenous regional anaesthesia during day case surgery.
AIMS To study the pharmacokinetics of articaine and its metabolite articainic acid, in patients undergoing intravenous regional… 
1997
1997
Epidural Metabolism of Articaine to its Metabolite Articainic Acid in Five Patients after Epidural Administration of 600 mg Articaine
The clinical pharmacokinetics, metabolism and renal excretion of articaine and its metabolite articainic acid have been… 
1996
1996
Saturable In Vitro Metabolism of Articaine by Serum Esterases: Does It Contribute to the Persistence of the Local Anesthetic Effect?
Background and Objectives The amide-type local anesthetic articaine is unique in that hydrolysis to articainic acid by serum… 
1993
1993
A simple method for the determination of articaine and its metabolite articainic acid in dentistry: application to a comparison of articaine and lidocaine concentrations in alveolus blood.
This study was undertaken to develop a time- and cost-effective method for the detection of articaine and articainic acid in… 
1989
1989
Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration.
Articaine is metabolized into articainic acid. The half-lives of articaine are 0.54 +/- 0.05 and 2.44 +/- 0.30 h and that of its… 
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