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2-aminofluorene

Known as: 2-fluorenamine, 2-fluorenylamine, 9H-fluoren-2-amine 
National Institutes of Health

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3 relations

Broader (3)

CarcinogensFluorenesMutagens

Papers overview

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Highly Cited
2001
Highly Cited
2001
Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH…
Highly Cited
1989
Highly Cited
1989
Differences in detection of DNA adducts in the 32P-postlabelling assay after either 1-butanol extraction or nuclease P1 treatment.
Highly Cited
1983
Highly Cited
1983
The oxidation of 2-aminofluorene by prostaglandin endoperoxide synthetase. Comparison with other peroxidases.
We have examined the prostaglandin endoperoxide synthetase-dependent metabolism of the arylamine carcinogen 2-aminofluorene (2-AF… 
Highly Cited
1983
Highly Cited
1983
Mixtures of polycyclic aromatic compounds inhibit mutagenesis in the Salmonella/microsome assay by inhibition of metabolic activation.
1983
1983
Conformation of 2‐aminofluorene‐modified DNA
Minimized potential‐energy calculations were performed to determine the conformation of the 2‐aminofluorene (AF) adduct to dCpdG… 
Highly Cited
1982
Highly Cited
1982
Cytochrome P-450- and flavin-containing monooxygenase-catalyzed formation of the carcinogen N-hydroxy-2-aminofluorene and its covalent binding to nuclear DNA.
The metabolic N-oxidation of the carcinogen 2-aminofluorene was examined in vitro using fortified hepatic microsomes from a… 
1981
1981
Partial persistency of 2-aminofluorene and N-acetyl-2-aminofluorene in rat liver DNA.
Male rats were treated with [ring-3H]N-acetyl-2-aminofluorene and sacrificed at different periods of time after a single i.p… 
Highly Cited
1977
Highly Cited
1977
Induction of sister chromatid exchanges in Chinese hamster cells by carcinogenic mutagens requiring metabolic activation.
Highly Cited
1972
Highly Cited
1972
N-acetoxy-N-acetylaminoarenes and nitrosoarenes. One-electron non-enzymatic and enzymatic oxidation products of various carcinogenic aromatic acethydroxamic acids.
Highly Cited
1965
Highly Cited
1965
Dehydroxylation and deacetylation of N-hydroxy-N-2-fluorenylacetamide by rat liver and brain homogenates.
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