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2-aminofluorene

Known as: 2-fluorenamine, 2-fluorenylamine, 9H-fluoren-2-amine 
 
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
Four polymorphic human cytochrome P450 (CYP) 1B1 allelic variants, namely Arg48,Ala119,Leu432,Asn453, Arg48,Ser119,Leu432,Asn453… Expand
Highly Cited
1996
Highly Cited
1996
A human cytochrome P-450 (P450) 1B1 cDNA was expressed in Saccharomyces cerevisiae and the microsomes containing P450 1B1 were… Expand
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Review
1994
Review
1994
2-Acetylaminofluorene and 2-aminofluorene are among the most intensively studied of all chemical mutagens and carcinogens… Expand
Highly Cited
1991
Highly Cited
1991
The metabolic activation of the food-borne rodent carcinogens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3,8… Expand
Highly Cited
1990
Highly Cited
1990
Acetyl-CoA: N-hydroxyarylamine O-acetyltransferase is an enzyme involved in the intracellular metabolic activation of… Expand
Highly Cited
1983
Highly Cited
1983
We have examined the prostaglandin endoperoxide synthetase-dependent metabolism of the arylamine carcinogen 2-aminofluorene (2-AF… Expand
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Highly Cited
1977
Highly Cited
1977
Uridine 5'-diphosphoglucuronic acid-fortified hepatic microsomes from dogs, rats, or humans rapidly metabolized [3H]-N-hydroxy-2… Expand
Highly Cited
1974
Highly Cited
1974
  • W. Durston, B. Ames
  • Proceedings of the National Academy of Sciences…
  • 1974
  • Corpus ID: 30260844
We described previously a simple test on petri plates for detecting many carcinogens as mutagens using an especially sensitive… Expand
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Highly Cited
1963
Highly Cited
1963
N -Hydroxy-2-acetylaminofluorene ( N -hydroxy-AAF), in conjugated form, was identified as a urinary metabolite of 2… Expand
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Highly Cited
1958
Highly Cited
1958
Publisher Summary This chapter describes the chemistry, carcinogenicity, and metabolism of 2-flurorenamine and related compounds… Expand