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2-amino-5-methylthiazole

Known as: 2a5mt cpd 
National Institutes of Health

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1 relation

Broader (1)

Thiazoles

Papers overview

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2019
2019
Solubility of solid intermediate of pharmaceutical compounds in pure organic solvents using semi-empirical models.
2017
2017
AMINO GROUP OF A PRIMARY AMINE BY A CHLORINE ATOM AND A SYNTHETIC METHOD BY APPLICATION THEREOF
Typically, a heterocyclic primary amine and Sodium nitrite are caused to react in the presence of hydrochloric acid, followed by… 
Highly Cited
2013
Highly Cited
2013
Calculating the binding free energies of charged species based on explicit-solvent simulations employing lattice-sum methods: an accurate correction scheme for electrostatic finite-size effects.
The calculation of a protein-ligand binding free energy based on molecular dynamics (MD) simulations generally relies on a… 
2008
2008
(Thermo)dynamic role of receptor flexibility, entropy, and motional correlation in protein-ligand binding.
The binding of 2-amino-5-methylthiazole to the W191G cavity mutant of cytochrome c peroxidase is an ideal test case to… 
2008
2008
Evaluación del Potencial Mutagénico de Piroxicam, Meloxicam y Precursores mediante el Ensayo de Micronúcleos in vivo
Mutagenic potential of piroxicam (1), 2-aminopyridine (2), meloxicam (3) and 2-amino-5-methylthiazole (4) has been evaluated… 
2003
2003
Improved synthesis of 2-amino-5-methylthiazole
2-Amino-5-methylthiazole,a key intermediate for the synthesis of meloxicam,was prepared from n-propanol by oxidation and… 
Highly Cited
2002
Highly Cited
2002
Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.
2002
2002
Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
Cavity complementation has been observed in many proteins, where an appropriate small molecule binds to a cavity-forming mutant… 
2002
2002
Study on the Synthesis and Using of 2-Amino-5-Methylthiazole
  • R. De
  • 2002
  • Corpus ID: 101416081
amino 5 methylthiazole (1) was prepared using 1,2,3 trichloropropane as starting material, which reacted with sodium hydroxide to… 
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