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2-Acetylaminofluorene

Known as: N-Acetyl-2-Aminofluorene, 2-Acetamidofluorene, Fluoren 2 ylacetamide 
A synthetic, light tan crystalline solid that is insoluble in water and soluble in alcohols, glycols, ether, acetic acid, and fat solvents. It is… 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
The expression of P-glycoprotein encoded by the multidrug resistance (MDR1) gene is associated with the emergence of the MDR… 
Highly Cited
1999
Highly Cited
1999
Bone marrow stem cells develop into hematopoietic and mesenchymal lineages but have not been known to participate in production… 
Highly Cited
1996
Highly Cited
1996
A human cytochrome P-450 (P450) 1B1 cDNA was expressed in Saccharomyces cerevisiae and the microsomes containing P450 1B1 were… 
Review
1994
Review
1994
Organic isothiocyanates block the production of tumors induced in rodents by diverse carcinogens (polycyclic aromatic… 
Review
1990
Review
1990
Chemicals that induce cancer at high doses in animal bioassays often fail to fit the traditional characterization of genotoxins… 
Highly Cited
1984
Highly Cited
1984
  • R. Gupta
  • Proceedings of the National Academy of Sciences…
  • 1984
  • Corpus ID: 22483575
We have examined the distribution of individual adducts in repetitive DNA sequences of rat liver in vivo after a single dose of… 
Review
1983
Review
1983
Glutathione (GSH) is a strong nucleophile which reacts well with soft electrophiles, but poorly with both weak and strong… 
Highly Cited
1972
Highly Cited
1972
Several carcinogenic metabolites of the carcinogen 2-acetyl-aminofluorene, especially 2-nitrosofluorene and N-hydroxy-2… 
Highly Cited
1971
Highly Cited
1971
Summary The effects of dietary phenobarbital on hepatocarcinogenesis in rats fed 2-acetylaminofluorene (AAF) were studied. The… 
Highly Cited
1961
Highly Cited
1961
Summary N-Hydroxy-2-acetylaminofluorene, a major metabolite of 2-acetylaminofluorene in the rat, was more active than the parent…