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2-Acetylaminofluorene:MCnc:Pt:Air:Qn

Known as: 2-Acetilaminofluoreto:MCnc:Pt:Ar:Qn, 2-AAF Air-mCnc, 2-Acetylaminofluorene [Mass/volume] in Air 
 
National Institutes of Health

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4 relations
2-AcetylaminofluoreneAir (substance)TwoUnit of Mass Concentration

Papers overview

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2013
2013
Role of epigenetic and miR‐22 and miR‐29b alterations in the downregulation of Mat1a and Mthfr genes in early preneoplastic livers in rats induced by 2‐acetylaminofluorene
Carcinogenesis is a multistep sequential process of clonal expansion of initiated cells associated with the accumulation of… Expand
Highly Cited
2003
Highly Cited
2003
Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene
A hallmark of tumorigenesis is resistance to apoptosis. To explore whether resistance to cell death precedes tumor formation, we… Expand
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Highly Cited
2002
Highly Cited
2002
Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-κB signaling
The expression of P-glycoprotein encoded by the multidrug resistance (MDR1) gene is associated with the emergence of the MDR… Expand
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Highly Cited
2001
Highly Cited
2001
2-Acetylaminofluorene Up-regulates Rat mdr1bExpression through Generating Reactive Oxygen Species That Activate NF-κB Pathway*
Overexpression of multidrug resistance genes and their encoded P-glycoproteins is a major mechanism for the development of… Expand
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1993
1993
Biphasic removal of DNA adducts in a repetitive DNA sequence after dietary administration of 2-acetylaminofluorene.
Dietary administration of the hepatocarcinogen 2-acetylaminofluorene (2-AAF) to rats results in the formation of a major hepatic… Expand
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1985
1985
Distribution of initial and persistent 2-acetylaminofluorene-induced DNA adducts within DNA loops.
The intranuclear distribution of initial and persistent DNA adducts induced in vivo after four weekly injections of the… Expand
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1984
1984
Induction of unscheduled DNA synthesis in primary cultures of rat pancreatic cells following in vivo and in vitro treatment with genotoxic agents.
The pancreas is a key target tissue in human and animal carcinogenesis, yet few short-term test systems measure genotoxicity in… Expand
1980
1980
Quantitative assessment of liver colony formation and hepatocellular carcinoma incidence in rats receiving intravenous injections of isogeneic liver cells isolated during hepatocarcinogenesis.
Abstract A quantitative procedure is described that utilized rat livers to measure a specific “liver colony-forming unit” (LV-CFU… Expand
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1975
1975
A comparison of the effects of 3'-methyl-4-dimethylaminoazobenzene, 2-methyl-4-dimethylaminoazobenzene, and 2-acetylaminofluorene on rat liver DNA stability and new synthesis.
The objective of the present study was to define early biochemical changes occuring in livers of rats that were fed various… Expand
1973
1973
Effects of 2-acetylaminofluorene on liver cell proliferation after partial hepatectomy of female rats.
The effect of the hepatocarcinogen 2-acetylaminofluorene (AAF) on liver regeneration in female Sprague-Dawley rats was studied… Expand
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