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2',3'-dideoxyadenosine triphosphate

Known as: 2',3'-dideoxy-ATP, ddATP 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Deoxyadenine NucleotidesDideoxynucleotides

Papers overview

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Highly Cited
2002
Highly Cited
2002
Crystal structures of a template‐independent DNA polymerase: murine terminal deoxynucleotidyltransferase
The crystal structure of the catalytic core of murine terminal deoxynucleotidyltransferase (TdT) at 2.35 Å resolution reveals a… 
Highly Cited
1996
Highly Cited
1996
A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta.
When crystals of human DNA polymerase beta (pol beta) complexed with DNA [Pelletier, H., Sawaya, M. R., Wolfle, W., Wilson, S. H… 
Highly Cited
1995
Highly Cited
1995
Enzymatic Characterization of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Resistant to Multiple 2′,3′-Dideoxynucleoside 5′-Triphosphates (*)
A set of five mutations (A62V, V75I, F77L, F116Y, and Q151M) in the polymerase domain of reverse transcriptase (RT) of human… 
Highly Cited
1994
Highly Cited
1994
Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase
A human immunodeficiency virus type 1 variant resistant to zalcitabine (2',3'-dideoxycytidine [ddC]) was selected by sequential… 
Highly Cited
1994
Highly Cited
1994
Functional reconstitution of wild-type and mutant Tetrahymena telomerase.
Telomerase is a ribonucleoprotein that catalyzes telomere elongation in vitro and in vivo. The 159-nucleotide RNA component of… 
Highly Cited
1993
Highly Cited
1993
Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.
The antiviral activity of azidothymidine (AZT), dideoxycytidine (ddC), and dideoxyinosine (ddI) against HIV-1 was comparatively… 
Highly Cited
1993
Highly Cited
1993
Identification of a nonprocessive telomerase activity from mouse cells.
Telomerase activity was identified in extracts from several different mouse cell lines. Addition of telomeric TTAGGG repeats was… 
Highly Cited
1990
Highly Cited
1990
Pharmacokinetics of 2′, 3′‐dideoxyadenosine and 2′, 3′‐dideoxyinosine in patients with severe human immunodeficiency virus infection
This article describes the pharmacokinetics of 2′,3′‐dideoxyadenosine (ddA) and 2′,3′‐dideoxyinosine (ddI) as determined during… 
Highly Cited
1989
Highly Cited
1989
Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy.
The muscle mitochondria of a patient with Kearns-Sayre/chronic external ophthalmoplegia plus syndrome were found to be completely… 
Highly Cited
1988
Highly Cited
1988
Sequence and organization of barley yellow dwarf virus genomic RNA.
The nucleotide sequence of the genomic RNA of barley yellow dwarf virus, PAV serotype was determined, except for the 5'-terminal… 
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