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2,6-dichlorobiphenyl

 
National Institutes of Health

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Polychlorinated Biphenyls

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2018
2018
Featured structure-activity relationships for some tri- and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity - Impact of the extent of ortho-chlorination.
Polychlorinated biphenyls (PCBs) as a group of persistent organic pollutants are confirmed human carcinogens; however, their… Expand
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2016
2016
Structural Basis of the Enhanced Pollutant-Degrading Capabilities of an Engineered Biphenyl Dioxygenase.
UNLABELLED Biphenyl dioxygenase, the first enzyme of the biphenyl catabolic pathway, is a major determinant of which… Expand
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2016
2016
Title : The structural basis of the enhanced pollutant-degrading capabilities of an engineered 1 biphenyl dioxygenase 2 Running Title : Structural Studies of BphAE variant II 9 3
20 Biphenyl dioxygenase, the first enzyme of the biphenyl catabolic pathway, is a major determinant of 21 which PCB congeners are… Expand
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2012
2012
Metabolites of 2,2'-dichlorobiphenyl and 2,6-dichlorobiphenyl in hairy root culture of black nightshade Solanum nigrum SNC-9O.
The hairy root culture of black nightshade (Solanum nigrum) SNC-9O was exposed to 2,2'-dichlorobiphenyl (PCB 4) and 2,6… Expand
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2011
2011
Biochemical studies and ligand-bound structures of biphenyl dehydrogenase from Pandoraea pnomenusa strain B-356 reveal a basis for broad specificity of the enzyme.
Biphenyl dehydrogenase, a member of short-chain dehydrogenase/reductase enzymes, catalyzes the second step of the biphenyl… Expand
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2011
2011
Structural insight into the expanded PCB-degrading abilities of a biphenyl dioxygenase obtained by directed evolution.
The biphenyl dioxygenase of Burkholderia xenovorans LB400 is a multicomponent Rieske-type oxygenase that catalyzes the… Expand
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2007
2007
Characterization of biphenyl dioxygenase of Pandoraea pnomenusa B-356 as a potent polychlorinated biphenyl-degrading enzyme.
Biphenyl dioxygenase (BPDO) catalyzes the aerobic transformation of biphenyl and various polychlorinated biphenyls (PCBs). In… Expand
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2002
2002
Family shuffling of a targeted bphA region to engineer biphenyl dioxygenase.
In this work we used a new strategy designed to reduce the size of the library that needs to be explored in family shuffling to… Expand
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1993
1993
Effects of polychlorinated biphenyl congener concentration and sediment supplementation on rates of methanogenesis and 2,3,6-trichlorobiphenyl dechlorination in an anaerobic enrichment.
We have employed a method of enrichment that allows us to significantly increase the rate of reductive polychlorinated biphenyl… Expand
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