2,4-pyrrolidine dicarboxylate

Known as: pyrrolidine-2,4-dicarboxylate 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2014
02419912014

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
An increased concentration of extracellular glutamate is associated with neuronal damage induced by cerebral ischemia. We have… (More)
Is this relevant?
2001
2001
Increased levels of extracellular excitatory amino acids and failure of energy metabolism are two conditions associated with… (More)
Is this relevant?
2001
2001
Several lines of evidence implicate excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis (ALS). Transgenic… (More)
Is this relevant?
2000
2000
Several enzymes with the capacity to degrade glutamate have been suggested as possible neuroprotectants. We initially evaluated… (More)
Is this relevant?
1999
1999
Transporters are thought to assist in the termination of synaptic transmission at some synapses by removing neurotransmitter from… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
1997
1997
This study examined the effects of chronic intrastriatal infusion of L-trans-pyrrolidine-2,4-dicarboxylate (PDC), a selective… (More)
Is this relevant?
1996
1996
We studied the early and late effects of L-trans-pyrrolidine-2,4-dicarboxylate (PDC), a competitive inhibitor of glutamate uptake… (More)
Is this relevant?
1996
1996
Because of the well-documented importance of glutamate uptake in protecting neurons against glutamate toxicity, we were… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
In order to determine the conformational requirements for binding of L-glutamate to the proteins involved in the process of… (More)
Is this relevant?