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2,4-pyrrolidine dicarboxylate

Known as: pyrrolidine-2,4-dicarboxylate 
National Institutes of Health

Papers overview

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2001
2001
Increased levels of extracellular excitatory amino acids and failure of energy metabolism are two conditions associated with… 
Highly Cited
2001
Highly Cited
2001
Several lines of evidence implicate excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis (ALS). Transgenic… 
Highly Cited
2000
Highly Cited
2000
Highly Cited
1999
Highly Cited
1999
Transporters are thought to assist in the termination of synaptic transmission at some synapses by removing neurotransmitter from… 
Highly Cited
1996
Highly Cited
1996
Because of the well‐documented importance of glutamate uptake in protecting neurons against glutamate toxicity, we were… 
Highly Cited
1996
Highly Cited
1996
We studied the early and late effects of L‐trans‐pyrrolidine‐2,4‐dicarboxylate (PDC), a competitive inhibitor of glutamate uptake… 
Highly Cited
1991
Highly Cited
1991
In order to determine the conformational requirements for binding of L-glutamate to the proteins involved in the process of…