2,4-diaminopteridine

Known as: 2,4-NH2-pteridine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2015
01219762015

Papers overview

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2015
2015
BACKGROUND Reactive oxygen species are associated with inflammation implicated in cancer, atherosclerosis and autoimmune diseases… (More)
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2012
2012
A series of 2-amino-[1,8]-naphthyridine-3-carboxamides (ANCs) with potent inhibition of bacterial NAD(+)-dependent DNA ligases… (More)
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2010
2010
A molecular docking study was carried out on 28 compounds belonging to 2,4-diaminoquinazoline and 2,4-diaminopteridine analogs… (More)
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2009
2009
Substituted 2,4-diaminopteridine derivatives 10a-10l were prepared in moderate to good yield. Their structures were confirmed by… (More)
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2009
2009
The crystal structure of the ternary complex of human dihydrofolate reductase (hDHFR) with NADPH and the Z isomer of 2,4-diamino… (More)
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2008
2008
Pteridine reductase (PTR1) is essential for salvage of pterins by parasitic trypanosomatids and is a target for the development… (More)
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2005
2005
We have tested the hypothesis that 2,4-diamino-6-hydroxymethyl-pteridine (DAP), 2,4-diaminopteroic acid (DAPA), and 2,4 diamino… (More)
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2004
2004
The activities of 28 6-substituted 2,4-diaminoquinazolines, 2,4-diamino-5,6,7,8-tetrahydroquinazolines, and 2,4-diaminopteridines… (More)
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1998
1998
Binding energy calculations for complexes of mutant and wild-type human dihydrofolate reductases with 2,4-diaminopteridine and 2… (More)
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1976
1976
Roswell Park Memorial Institute 4265 human lymphoblasts were grown with three dihydrofolate reductase inhibitors: a 2,4… (More)
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