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2,4,4-trimethyl-2-pentanol

National Institutes of Health

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Pentanols

Papers overview

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2007
2007
Identification of opdA, a Gene Involved in Biodegradation of the Endocrine Disrupter Octylphenol
ABSTRACT Octylphenol (OP) is an estrogenic detergent breakdown product. Structurally similar nonylphenols are transformed via… 
1999
1999
A physiological model for ligand-induced accumulation of alpha 2u globulin in male rat kidney: roles of protein synthesis and lysosomal degradation in the renal dosimetry of 2,4,4-trimethyl-2…
1995
1995
Development of a mechanism-based dosimetry model for 2,4,4-trimethyl-2-pentanol-induced alpha 2u-globulin nephropathy in male Fischer 344 rats.
A mechanism-based dosimetry model was developed to describe 2,4,4-trimethyl-2-pentanol (TMP-2-OH) dosimetry and renal alpha 2u… 
1994
1994
Use of primary rat proximal tubule fragments for study of α2u-globulin, 2,5-dichlorophenol, and 2,4,4-trimethyl-2-pentanol toxicity
1993
1993
Assessment of binding of 2,4,4-trimethyl-2-pentanol to low-molecular-weight proteins isolated from kidneys of male rats and humans.
A number of chemicals cause a nephrotoxic syndrome in male rats, referred to as protein droplet or alpha 2u-globulin (alpha 2u… 
Highly Cited
1991
Highly Cited
1991
Characteristics of chemical binding to alpha 2u-globulin in vitro--evaluating structure-activity relationships.
Highly Cited
1987
Highly Cited
1987
2,2,4-Trimethylpentane-induced nephrotoxicity. I. Metabolic disposition of TMP in male and female Fischer 344 rats.
1985
1985
Identification of urinary metabolites of the nephrotoxic hydrocarbon 2,2,4-trimethylpentane in male rats.
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