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Triterpenes are one of the largest classes of plant metabolites and have important functions. A diverse array of triterpenoid… Expand Glycyrrhizin, a major bioactive compound derived from the underground parts of Glycyrrhiza (licorice) plants, is a triterpene… Expand In higher organisms the formation of the steroid scaffold is catalysed exclusively by the membrane-bound oxidosqualene cyclase… Expand Many different plant species synthesise triterpenoid saponins as part of their normal programme of growth and development… Expand 2,3-Oxidosqualene:lanosterol cyclase (OSC, E.C. 22.214.171.124) represents a unique target for a cholesterol lowering drug. Partial… Expand The crystal structure of squalene-hopene cyclase from Alicyclobacillus acidocaldarius was determined at 2.9 angstrom resolution… Expand The ERG7 gene encoding oxidosqualene-lanosterol cyclase [(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol forming), EC 5.4.99… Expand Monocyclic and tricyclic compounds possessing a nitrogen atom situated at a position corresponding to the carbenium ion of high… Expand Mutants of Saccharomyces cerevisiae were isolated which were blocked in heme biosynthesis and required heme for growth on a… Expand Abstract An enzyme catalyzing the anaerobic cyclization of 2,3-oxidosqualene into lanosterol has been extracted from hog liver… Expand