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2,3-oxidosqualene

Known as: squalene-2,3-epoxide, 2,3-EDSQ, 2,3-epoxy-2,3-dihydrosqualene 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Triterpenes are one of the largest classes of plant metabolites and have important functions. A diverse array of triterpenoid… Expand
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Highly Cited
2008
Highly Cited
2008
Glycyrrhizin, a major bioactive compound derived from the underground parts of Glycyrrhiza (licorice) plants, is a triterpene… Expand
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Highly Cited
2004
Highly Cited
2004
In higher organisms the formation of the steroid scaffold is catalysed exclusively by the membrane-bound oxidosqualene cyclase… Expand
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Review
2002
Review
2002
Many different plant species synthesise triterpenoid saponins as part of their normal programme of growth and development… Expand
Highly Cited
1997
Highly Cited
1997
2,3-Oxidosqualene:lanosterol cyclase (OSC, E.C. 5.4.99.7) represents a unique target for a cholesterol lowering drug. Partial… Expand
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Highly Cited
1997
Highly Cited
1997
The crystal structure of squalene-hopene cyclase from Alicyclobacillus acidocaldarius was determined at 2.9 angstrom resolution… Expand
Highly Cited
1994
Highly Cited
1994
The ERG7 gene encoding oxidosqualene-lanosterol cyclase [(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol forming), EC 5.4.99… Expand
1992
1992
Monocyclic and tricyclic compounds possessing a nitrogen atom situated at a position corresponding to the carbenium ion of high… Expand
Highly Cited
1977
Highly Cited
1977
Mutants of Saccharomyces cerevisiae were isolated which were blocked in heme biosynthesis and required heme for growth on a… Expand
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Highly Cited
1967
Highly Cited
1967
Abstract An enzyme catalyzing the anaerobic cyclization of 2,3-oxidosqualene into lanosterol has been extracted from hog liver… Expand