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2,2'-pyridylisatogen tosylate

 
National Institutes of Health

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3 relations

Broader (2)

IsatinPurinergic P2 Receptor Antagonists
analogs & derivatives

Papers overview

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2008
2008
Novel consequences of voltage‐dependence to G‐protein‐coupled P2Y1 receptors
Emerging evidence suggests that activation of G‐protein‐coupled receptors (GPCRs) can be directly regulated by membrane voltage… Expand
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2004
2004
2,2'-Pyridylisatogen tosylate antagonizes P2Y1 receptor signaling without affecting nucleotide binding.
The effect of 2,2'-pyridylisatogen tosylate (PIT) on the human P2Y(1) receptor and on other recombinant P2Y receptors has been… Expand
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2002
2002
Role of spin trapping and P2Y receptor antagonism in the neuroprotective effects of 2,2'-pyridylisatogen tosylate and related compounds.
2,2'-Pyridylisatogen tosylate (PIT) is both an allosteric modulator of P2Y receptors, and an immine oxide, acting as a spin trap… Expand
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1997
1997
Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: potentiation by 2,2′‐pyridylisatogen tosylate
1 Vasoconstrictions induced by transmural electrical field stimulation were frequency‐dependent from 2 to 32 Hz in the rabbit… Expand
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1996
1996
Potentiation by 2,2′‐pyridylisatogen tosylate of ATP‐responses at a recombinant P2Y1 purinoceptor
1 2,2′‐Pyridylisatogen tosylate (PIT) has been reported to be an irreversible antagonist of responses to adenosine 5… Expand
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1993
1993
Prior glucose deprivation increases the first phase of glucose-induced insulin response: possible involvement of endogenous ATP and (or) ADP.
A possible implication of endogenously released ATP and (or) ADP in insulin response to glucose stimulation was investigated in… Expand
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1985
1985
The mechanism of inhibition by 2,2'-pyridylisatogen tosylate of NADPH-linked enzyme activities in microsomes isolated from rat liver.
Microsomal preparations isolated from rat liver were used to study the action of 2.2'-pyridylisatogen tosylate (PIT) on aniline… Expand
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1983
1983
Modulation of guinea-pig peritoneal macrophage Fc receptor activity using D-penicillamine.
The influence of D-penicillamine and 2,2'-pyridylisatogen tosylate upon guinea-pig peritoneal IgG Fc receptor activity is… Expand
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1978
1978
The problems associated with the use of 2,2'-pyridylisatogen tosylate in evaluating the allegedly purinergic innervation of peripheral organs.
 
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