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2'-methyl-2'-deoxyidenecytidine

Known as: 1-(2-deoxy-2-methylene-erythro-pentofuranosyl)cytidine, 2'-deoxy-2'-methylenecytidine, 2'-deoxy-2'-methylidenecytidine 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
PURPOSE To develop a semimechanistic pharmacokinetic-pharmacodynamic model describing chemotherapy-induced myelosuppression… 
2001
2001
We studied mutational events in deoxycytidine (dCyd) kinase mRNA expression, focusing on aberrant dCyd kinase mRNA, which has… 
Highly Cited
2000
Highly Cited
2000
Abstract. Objective: DMDC (2'-deoxy-2'-methylidenecytidine) is a potential antitumour deoxycytidine analogue of cytosine… 
1998
1998
2'-Deoxy-2'-methylidenecytidine (DMDC) is a new 2'-deoxycytidine (dCyd) antimetabolite. The present study compared its antitumor… 
1998
1998
(E)-2'-deoxy-2'-(fluoromethylene) cytidine (MDL101,731) is a new deoxycytidine analog which shows potent antitumor activity… 
Highly Cited
1991
Highly Cited
1991
It has been found that 2'-deoxy-2'-methyleneuridine (MdUrd), 2'-deoxy-2'-methylenecytidine (MdCyd), and 2'-deoxy-2',2… 
Highly Cited
1991
Highly Cited
1991
A new type of antineoplastic nucleoside, 2'-deoxy-2'-methylidenecytidine (DMDC) has been synthesized from the corresponding 2… 
Highly Cited
1991
Highly Cited
1991
The antitumor activity of 2'-deoxy-2'-methylidenecytidine (DMDC), an inhibitor of DNA synthesis, was examined and compared with… 
1991
1991
Various 2'- and 3'-methylidene-substituted nucleoside analogues have been synthesized and evaluated as potential anticancer and… 
Highly Cited
1988
Highly Cited
1988
Le compose du titre est prepare a partir de l'uridine et du methylene trimethyl phosphorane. L'activite anticancereux est etudiee…