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2'-deoxythymidine-5'-monophosphate

 
National Institutes of Health

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2015
2015
ThyX is an essential thymidylate synthase that is mechanistically and structurally unrelated to the functionally analogous human… Expand
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2015
2015
The enzyme thymidylate synthase (TSase), an important chemotherapeutic drug target, catalyzes the formation of 2'-deoxythymidine… Expand
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2014
2014
Thymidylate synthase ThyX, required for DNA synthesis in many pathogenic bacteria, is considered a promising antimicrobial target… Expand
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2011
2011
Human thymidylate synthase (hTS) is an established anticancer target. It catalyses the production of 2'-deoxythymidine-5… Expand
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Review
2002
Review
2002
Thymidylate synthase (TS) is a key enzyme in the de novo synthesis of 2'-deoxythymidine-5'-monophosphate (dTMP) from 2… Expand
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Review
2002
Review
2002
Thymidylate synthase (TS) is a key enzyme in the synthesis of 2'-deoxythymidine-5'-monophosphate, an essential precursor for DNA… Expand
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2001
2001
We investigated the separation of five deoxyribonucleoside monophosphates: 2'-deoxyguanosine-5'-monophosphate (dGMP), 2… Expand
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1996
1996
Three steps along the pathway of binding, orientation of substrates and release of products are revealed by X-ray… Expand
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1984
1984
The mode of action of 5-fluorouracil (FUra) and 5-fluoro-2'-deoxyuridine (FdUrd) on L1210 leukaemia has been studied. It is shown… Expand
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1975
1975
In an attempt to differentiate between thymidine kinase (EC.2.4.1.21) induced by herpesvirus hominis type I (TK I) and type 2… Expand
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