2',6'-dimethyltyrosine

Known as: 2,6-dimethyltyrosine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2016
024619922016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
To synthesize potent antagonists of the mu-opioid receptor, we prepared a series of endomorphin-1 and endomorphin-2 analogues… (More)
Is this relevant?
2006
2006
Two new 99mTc-labeled neurotensin(8-13) analogues containing the retro-N(alpha)-carboxymethyl-histidine ((N(alpha)His)Ac… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Oxidative stress and mitochondrial oxidative damage have been implicated in aging and many common diseases. Mitochondria are a… (More)
Is this relevant?
2003
2003
Oligopeptides are generally thought to have poor permeability across biological membranes. Recent studies, however, suggest… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2003
2003
[Dmt1]DALDA (H-Dmt-d-Arg-Phe-Lys-NH2; Dmt = 2',6'-dimethyltyrosine) binds with high affinity and selectivity to the mu opioid… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
2002
2002
We recently discovered an opioid peptide analgesic, 2',6'-dimethyltyrosine (Dmt)-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), that can… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2001
2001
Recent studies showed that dermorphin and enkephalin analogues containing two methyl groups at the 2',6'-positions of the Tyr(1… (More)
Is this relevant?
2000
2000
The tetrapeptide DALDA (H-Tyr-D-Arg-Phe-Lys-NH2) is a polar and selective mu agonist showing poor penetration of the placental… (More)
Is this relevant?
1999
1999
Opioid compounds with mixed mu agonist/delta antagonist properties are expected to be analgesics with low propensity to produce… (More)
Is this relevant?
1992
1992
In order to develop systemically-active opioid peptides, the delta-selective, opioid pentapeptide [D-Pen2,D-Pen5]-enkephalin… (More)
Is this relevant?