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2',3'-dideoxyuridine

 
National Institutes of Health

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Broader (1)

Dideoxynucleosides

Papers overview

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2015
2015
Nucleoside Mono‐ and Diphosphate Prodrugs of 2′,3′‐Dideoxyuridine and 2′,3′‐Dideoxy‐2′,3′‐didehydrouridine
Despite their close structural similarity to nucleoside analogues such as the anti‐HIV drugs AZT and d4T, 2′,3′‐dideoxyuridine… Expand
2009
2009
An investigation into the anti-HIV activity of 2',3'-didehydro-2',3'-dideoxyuridine (d4U) and 2',3'-dideoxyuridine (ddU) phosphoramidate 'ProTide' derivatives.
As part of our studies on the anti-HIV activities of 2',3'-didehydro-2',3'-dideoxyuridine (d4U), 2',3'-dideoxyuridine (ddU) and… Expand
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2008
2008
Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state.
The conformations of three 2',3'-difluoro uridine nucleosides were studied by X-ray crystallography, NMR spectroscopy, and ab… Expand
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2007
2007
Design, synthesis, and anti-HIV activity of 2',3'-didehydro-2',3'-dideoxyuridine (d4U), 2',3'-dideoxyuridine (ddU) phosphoramidate 'ProTide' derivatives.
We report the synthesis of 2',3'-didehydro-2',3'-dideoxyuridine (d4U) and 2',3'-dideoxyuridine (ddU) phosphoramidate 'ProTide… Expand
Highly Cited
1996
Highly Cited
1996
Inhibition of Trypanosoma cruzi growth in mammalian cells by purine and pyrimidine analogs.
Trypanosoma cruzi, the causative agent of Chagas' disease, exhibits two different developmental stages in mammals, the amastigote… Expand
1993
1993
Inhibition of HIV-1 replication in cultured cells with phosphorylated dideoxyuridine derivatives encapsulated in immunoliposomes.
Among the 2',3'-dideoxynucleoside 5'-triphosphates containing a physiological base, 2',3'-dideoxyuridine 5'-triphosphate (ddUTP… Expand
1990
1990
5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity.
5'-O-Phosphonomethylation of different pyrimidine 2',3'-dideoxynucleosides was accomplished by reaction of the latter with… Expand
1989
1989
Production of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine from 2',3'-dideoxyuridine and the corresponding purine bases by resting cells of Escherichia coli AJ 2595.
A novel microbial method for the production of 2',3'-dideoxynucleosides by transdideoxyribosylation has been developed. By… Expand
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Highly Cited
1989
Highly Cited
1989
Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus.
Analysis of the solid-state conformations of six active and two inactive anti-human immunodeficiency virus nucleoside analogues… Expand
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Highly Cited
1988
Highly Cited
1988
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
The 3'-fluoro-and 3'-azido-substituted derivatives of 2',3'-dideoxythymidine (ddThd), 2',3'-dideoxyuridine (ddUrd), 2',3'-dideoxy… Expand
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