2',3'-dideoxyuridine
National Institutes of Health
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Despite their close structural similarity to nucleoside analogues such as the anti‐HIV drugs AZT and d4T, 2′,3′‐dideoxyuridine…
As part of our studies on the anti-HIV activities of 2',3'-didehydro-2',3'-dideoxyuridine (d4U), 2',3'-dideoxyuridine (ddU) and…
The conformations of three 2',3'-difluoro uridine nucleosides were studied by X-ray crystallography, NMR spectroscopy, and ab…
A summary of the most recent advances to the design of pronucleotides will be presented. Approaches that have been designed to be…
5'-O-Phosphonomethylation of different pyrimidine 2',3'-dideoxynucleosides was accomplished by reaction of the latter with…
Analysis of the solid-state conformations of six active and two inactive anti-human immunodeficiency virus nucleoside analogues…
A novel microbial method for the production of 2',3'-dideoxynucleosides by transdideoxyribosylation has been developed. By…