Skip to search form
Skip to main content
>
Semantic Scholar
Semantic Scholar's Logo
Search
Sign In
Create Free Account
You are currently offline. Some features of the site may not work correctly.
2',3'-dideoxythymidine
National Institutes of Health
Create Alert
Related topics
Related topics
1 relation
Broader (1)
Dideoxynucleosides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine.
X. Kong
,
Q. Y. Zhu
,
+6 authors
T. Chou
Antimicrobial Agents and Chemotherapy
1991
Corpus ID: 10083923
The effects of 3'-azido-3'-deoxythymidine (AZT), phosphonoformate (PFA), and 2',3'-dideoxythymidine (ddT) and their combination…
Expand
1989
1989
Production of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine from 2',3'-dideoxyuridine and the corresponding purine bases by resting cells of Escherichia coli AJ 2595.
H. Shirae
,
K. Kobayashi
,
H. Shiragami
,
Y. Irie
,
N. Yasuda
,
K. Yokozeki
Applied and environmental microbiology
1989
Corpus ID: 10809118
A novel microbial method for the production of 2',3'-dideoxynucleosides by transdideoxyribosylation has been developed. By…
Expand
Highly Cited
1988
Highly Cited
1988
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
J. Balzarini
,
M. Baba
,
R. Pauwels
,
P. Herdewijn
,
E. de Clerq
Biochemical pharmacology
1988
Corpus ID: 33677177
The 3'-fluoro-and 3'-azido-substituted derivatives of 2',3'-dideoxythymidine (ddThd), 2',3'-dideoxyuridine (ddUrd), 2',3'-dideoxy…
Expand
Highly Cited
1988
Highly Cited
1988
Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.
Z. Hao
,
D. Cooney
,
+6 authors
D. Johns
Molecular pharmacology
1988
Corpus ID: 24209019
Mitsuya and Broder [Proc. Natl. Acad. Sci. USA 83:1911-1915 (1986)] demonstrated that every purine (adenosine, guanosine, and…
Expand
Highly Cited
1987
Highly Cited
1987
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
M. Baba
,
R. Pauwels
,
P. Herdewijn
,
E. de Clercq
,
J. Desmyter
,
M. Vandeputte
Biochemical and biophysical research…
1987
Corpus ID: 12822355
2',3'-Dideoxythymidine (ddThd) and its 2',3'-unsaturated derivative 2',3'-dideoxythymidinene (ddeThd) are potent and selective…
Expand
Highly Cited
1987
Highly Cited
1987
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
P. Herdewijn
,
J. Balzarini
,
+4 authors
H. Vanderhaeghe
Journal of medicinal chemistry
1987
Corpus ID: 39903494
A series of 2',3'-unsaturated and 3'-substituted 2',3'-dideoxynucleoside analogues of purines and pyrimidines have been…
Expand
1985
1985
Effects of aphidicolin and/or 2',3'-dideoxythymidine on DNA repair induced in HeLa cells by four types of DNA-damaging agents.
K. Yamada
,
F. Hanaoka
,
M. Yamada
The Journal of biological chemistry
1985
Corpus ID: 9777155
The alkaline sucrose density gradient centrifugation method was modified to permit detection of 1 lesion/10(9) daltons of DNA…
Expand
Highly Cited
1980
Highly Cited
1980
Acyclovir inhibition of Epstein-Barr virus replication.
A. K. Datta
,
B. Colby
,
J. E. Shaw
,
J. Pagano
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 36522999
Acyclovir [9-(2-hydroxyethoxymethyl)guanine] triphosphate inhibits Epstein-Barr virus (EBV)-associated DNA polymerase (DNA…
Expand
Highly Cited
1979
Highly Cited
1979
Involvement of eucaryotic deoxyribonucleic acid polymerases alpha and gamma in the replication of cellular and viral deoxyribonucleic acid.
H. Krokan
,
P. Schaffer
,
M. DePamphilis
Biochemistry
1979
Corpus ID: 32864983
In an effort to identify the deoxyribonucleic acid (DNA) polymerase activities responsible for mammalian viral and cellular DNA…
Expand
1975
1975
DNA chain termination by 2',3'-dideoxythymidine in replicating mammalian cells.
N. Byars
,
C. Kidson
Biochemistry
1975
Corpus ID: 38776324
The thymidine analog, 2,3-dideoxythymidine (ddT), is rapidly phosphorylated and incorporated terminally at 3-ends of growing DNA…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE