19-nordeoxycorticosterone

The most important mineralocorticoid produced by some fish, and most amphibians, reptiles, birds and mammals is aldosterone… Expand

19-Nordeoxycorticosterone (19-norDOC) is a powerful mineralocorticoid, which has been postulated to be involved in the… Expand

Rats susceptible to the hypertensive effect of dietary salt (SS/Jr) have excess urinary 19-nordeoxycorticosterone compared with… Expand

19-Nordeoxycorticosterone (19-norDOC) is a powerful mineralocorticoid that has been postulated to play a role in the pathogenesis… Expand

Increased mineralocorticoid activity has been associated with elevated urinary levels of 19-nordeoxycorticosterone in several… Expand

Rats were selectively bred for susceptibility (S) and resistance (R) to the hypertensinogenic effects of excess salt intake by… Expand

Adrenal enucleation (removal of the adrenal gland, leaving the capsule intact) results in regeneration of the adrenal cortex… Expand

Both 19-nordeoxycorticosterone and 19-norprogesterone are potent hypertensogens. This particularly interesting in the latter case… Expand

Excess mineralocorticoid activity is thought to be responsible for the increased sodium reabsorption found after adrenal… Expand

The effect of absence of the C-19 methyl group from five adrenal steroids has been studied in terms of their affinity for… Expand