18-Hydroxycorticosterone

CONTEXT Diagnosis of primary aldosteronism (PA) is made by screening, confirmation testing, and subtype diagnosis (computed… Expand

In primary hyperaldosteronism, discriminating bilateral adrenal hyperplasia (BAH) from an aldosterone-producing adenoma (APA) is… Expand

Corticosterone methyloxidase II (CMO-II) deficiency is an autosomal recessive disorder of aldosterone biosynthesis, characterized… Expand

A cDNA clone encoding human aldosterone synthase cytochrome P-450 (P-450aldo) has been isolated from a cDNA library derived from… Expand

The effects of sc injections (at 1500 h) of increasing amounts of synthetic human ACTH-(1-39) (1.25-30 micrograms) on plasma ACTH… Expand

In a prospective study of 80 patients with primary aldosteronism (70 with adenoma and 10 with hyperplasia), "refractory… Expand

Aldosterone-biosynthesizing adrenal tissue contains an angular methyl oxidase which converts corticosterone to 18… Expand

This study investigates the dopaminergic mechanisms involved in the control of corticosteroid secretion in normal subjects. TSH… Expand

Abstract We performed computed tomography (CT) in 22 consecutive patients with primary aldosteronism to evaluate the usefulness… Expand

Plasma 18-hydroxycorticosterone (180HB) concentration was measured in 23 patients with primary aldosteronism. After overnight… Expand