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18,19-dihydroetorphine

Known as: Dihydroetorphine 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Analgesics, OpioidEtorphine
analogs & derivatives

Narrower (1)

dihydroetorphine hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Targeting multiple opioid receptors – improved analgesics with reduced side effects?
Classical opioid analgesics, including morphine, mediate all of their desired and undesired effects by specific activation of the… Expand
Review
2004
Review
2004
The orvinols and related opioids--high affinity ligands with diverse efficacy profiles.
The thevinols and orvinols derived from thebaine via the thebaine-methylvinyl ketone adduct (thevinone) were thoroughly… Expand
2002
2002
Cell death-inducing activity of opiates in human oral tumor cell lines.
In screening cytotoxic agents in morphine alkaloids [TE1-10], codeinone [TE8] was cytotoxic against two human oral tumor cells… Expand
2000
2000
Sedative Tolerance Accompanies Tolerance to the Analgesic Effects of Fentanyl in Infant Rats
Iatrogenic tolerance and physical dependence have been documented in human neonates and infants infused with fentanyl or morphine… Expand
1999
1999
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors.
This study examines the possibility that oripavine opioid receptor agonists bind equally to both high and low affinity states of… Expand
Highly Cited
1997
Highly Cited
1997
Mu opioid receptor phosphorylation, desensitization, and ligand efficacy.
Mu opioid receptors are subject to phosphorylation and desensitization through actions of at least two distinct biochemical… Expand
Highly Cited
1997
Highly Cited
1997
Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity.
Comparative analgesic studies revealed that dihydroetorphine was more potent than etorphine in the tail-flick and hot-plate tests… Expand
Highly Cited
1994
Highly Cited
1994
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence
At low (< nM) concentrations, mu, delta or kappa opioid peptides as well as morphine and other opioid alkaloids elicit dose… Expand
1993
1993
Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in mice.
The profile of actions of dihydroetorphine (DHE) concerning antinociception, tolerance and dependence was compared with those of… Expand
1982
1982
[Analgesic and other CNS depressive effects of dihydroetorphine (author's transl)].
  • M. Huang, B. Qin
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1982
    • Corpus ID: 31694504
The analgesic, respiratory depressive, immobilizing effects and a cute toxicity of dihydroetorphine (DHE) have been evaluated and… Expand
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