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167B indolizidine

Known as: indolizidine 167B 
 
National Institutes of Health

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Indolizines

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2015
2015
Exposure to swainsonine impairs adult neurogenesis and spatial learning and memory.
Swainsonine (SW) is an indolizidine triol plant alkaloid isolated from the species Astragalus, colloquially termed locoweed… Expand
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2012
2012
The occurrence of defensive alkaloids in non-integumentary tissues of the Brazilian red-belly toad Melanophryniscus simplex (Bufonidae)
The red-belly toads (Melanophryniscus) of southern South America secrete defensive alkaloids from dermal granular glands. To date… Expand
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2012
2012
A diastereoselective cyclic imine cycloaddition strategy to access polyhydroxylated indolizidine skeleton: concise syntheses of (+)-/(-)-lentiginosines and (-)-2-epi-steviamine.
We describe in this paper the development of a novel diastereoselective cyclic imine cycloaddition strategy to access the… Expand
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2012
2012
Swainsonine as a lysosomal toxin affects dopaminergic neurons
Swainsonine (SW) is an indolizidine triol plant alkaloid isolated from the species Astragalus, colloquially termed locoweed. When… Expand
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2009
2009
Polyhydroxylated indolizidine alkaloidsdsynthesis of dideoxycastanospermine
The key transformation developed in this work is the anti-Kishi selective dihydroxylation, which proceeds by way of… Expand
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2008
2008
Analogues of amphibian alkaloids: total synthesis of (5R,8S,8aS)-(-)-8-methyl-5-pentyloctahydroindolizine (8-epi-indolizidine 209B) and [(1S,4R,9aS)-(-)-4-pentyloctahydro-2H-quinolizin-1-yl]methanol
BACKGROUND Prior work from these laboratories has centred on the development of enaminones as versatile intermediates for the… Expand
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Review
2007
Review
2007
Phytochemicals: the good, the bad and the ugly?
Phytochemicals are constitutive metabolites that enable plants to overcome temporary or continuous threats integral to their… Expand
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2004
2004
Alkaloids Indolizidine 235 B , Quinolizidine 1-epi-207 I , and the Tricyclic 205 B are Potent and Selective Noncompetitive Inhibitors of Nicotinic Acetylcholine Receptors
Nicotinic acetylcholine receptors are key molecules in cholinergic transmission in the nervous system. Because of their… Expand
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2003
2003
A flexible approach toward trisubstituted piperidines and indolizidines: synthesis of 6-epi-indolizidine 223A.
2,5,6-Trisubstituted piperidines are readily prepared by a combination of an aza-Achmatowicz oxidation of a furyl-substituted… Expand
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