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167B indolizidine

Known as: indolizidine 167B 
 
National Institutes of Health

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Indolizines

Papers overview

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2015
2015
Exposure to swainsonine impairs adult neurogenesis and spatial learning and memory.
Swainsonine (SW) is an indolizidine triol plant alkaloid isolated from the species Astragalus, colloquially termed locoweed… Expand
2012
2012
A diastereoselective cyclic imine cycloaddition strategy to access polyhydroxylated indolizidine skeleton: concise syntheses of (+)-/(-)-lentiginosines and (-)-2-epi-steviamine.
We describe in this paper the development of a novel diastereoselective cyclic imine cycloaddition strategy to access the… Expand
2012
2012
The occurrence of defensive alkaloids in non-integumentary tissues of the Brazilian red-belly toad Melanophryniscus simplex (Bufonidae)
The red-belly toads (Melanophryniscus) of southern South America secrete defensive alkaloids from dermal granular glands. To date… Expand
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2012
2012
Swainsonine as a lysosomal toxin affects dopaminergic neurons
Swainsonine (SW) is an indolizidine triol plant alkaloid isolated from the species Astragalus, colloquially termed locoweed. When… Expand
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2009
2009
Polyhydroxylated indolizidine alkaloidsdsynthesis of dideoxycastanospermine
The key transformation developed in this work is the anti-Kishi selective dihydroxylation, which proceeds by way of… Expand
2008
2008
Analogues of amphibian alkaloids: total synthesis of (5R,8S,8aS)-(−)-8-methyl-5-pentyloctahydroindolizine (8-epi-indolizidine 209B) and [(1S,4R,9aS)-(−)-4-pentyloctahydro-2H-quinolizin-1-yl]methanol
Background Prior work from these laboratories has centred on the development of enaminones as versatile intermediates for the… Expand
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Review
2007
Review
2007
Phytochemicals: the good, the bad and the ugly?
Phytochemicals are constitutive metabolites that enable plants to overcome temporary or continuous threats integral to their… Expand
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2004
2004
Alkaloids Indolizidine 235 B , Quinolizidine 1-epi-207 I , and the Tricyclic 205 B are Potent and Selective Noncompetitive Inhibitors of Nicotinic Acetylcholine Receptors
Nicotinic acetylcholine receptors are key molecules in cholinergic transmission in the nervous system. Because of their… Expand
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2003
2003
A flexible approach toward trisubstituted piperidines and indolizidines: synthesis of 6-epi-indolizidine 223A.
2,5,6-Trisubstituted piperidines are readily prepared by a combination of an aza-Achmatowicz oxidation of a furyl-substituted… Expand
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