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16,16-Dimethyl Prostaglandin E2

Known as: dmPGE2 
A stable derivative of prostaglandin E2 (PGE2) with potential hematopoietic activity. Administration of 16,16 dimethyl-prostaglandin E2 (dmPGE2… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Umbilical cord blood (UCB) is a valuable source of hematopoietic stem cells (HSCs) for use in allogeneic transplantation. Key… Expand
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Highly Cited
2011
Highly Cited
2011
Hematopoietic stem cells (HSCs) are used in transplantation therapy to reconstitute the hematopoietic system. Human cord blood… Expand
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Highly Cited
2004
Highly Cited
2004
Prostaglandin E2 (PGE2) synthesis modulates the response to radiation injury in the mouse intestinal epithelium through effects… Expand
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Highly Cited
2002
Highly Cited
2002
We evaluated the effect of various PGE analogs specific to EP receptor subtypes on indomethacin-induced small intestinal lesions… Expand
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Highly Cited
1997
Highly Cited
1997
Prostaglandins are synthesized from arachidonic acid by the enzyme cyclo-oxygenase. There are two isoforms of cyclooxygenases… Expand
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1987
1987
16,16-Dimethyl prostaglandin E2 (DiPGE2), a stable analog of PGE2, increases the LD50/30 survival in CD2F1 male mice when given… Expand
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1986
1986
We used in vivo microscopy and laser-Doppler velocimetry to examine the effects on the gastric mucosal microcirculation and in… Expand
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Highly Cited
1984
Highly Cited
1984
The effect of 16,16-dimethyl prostaglandin E2 (dmPGE2) on histologic and microcirculatory changes in alcohol-induced gastric… Expand
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Highly Cited
1981
Highly Cited
1981
We made direct measurements of the thickness of the layer of insoluble gel mucus lying on the gastric mucosa by using a slit lamp… Expand
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1980
1980
These studies were designed to compare intravenous and topical 16,16-dimethyl prostaglandin E2 (dmPGE2) as stimulants of gastric… Expand
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