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16,16-Dimethyl Prostaglandin E2

Known as: dmPGE2 
A stable derivative of prostaglandin E2 (PGE2) with potential hematopoietic activity. Administration of 16,16 dimethyl-prostaglandin E2 (dmPGE2… 
National Institutes of Health

Papers overview

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1999
1999
Prostaglandin E 2-Induced Up-Regulation of c-fos Messenger Ribonucleic Acid Is Primarily Mediated by 3 * , 5 *-Cyclic Adenosine Monophosphate in MC 3 T 3E 1 Osteoblasts *
The mechanism by which the proto-oncogene, c-fos, is up-regulated in response to PGE2 in the mouse osteoblastic (MC3T3-E1) cell… 
1987
1987
16,16-Dimethyl prostaglandin E2 protects gastric mucosal surface epithelial cells from indomethacin-induced damage in rats.
The protective effect of 16,16-dimethyl prostaglandin E2 (dmPGE2) against early damage induced by indomethacin in the rat gastric… 
1986
1986
Effect of cimetidine on indomethacin-induced damage in cultured rat gastric mucosal cells; comparison with prostaglandin.
Whether cimetidine protects gastric mucosal cells independently of its antisecretory effect has been controversial. Some… 
1986
1986
Pharmacokinetics of cyclosporine in toxicological studies.
Pharmacokinetic studies performed in toxicological studies indicate that CsA is well absorbed in rats and dogs with absolute… 
1986
1986
The phospholipid contents in rat liver Golgi-rich membrane fractions after streptozotocin and/or prostaglandin treatment.
After dmPGE2 treatment, both alone or together with streptozotocin, the lower, statistically significant total PL contents (in… 
1985
1985
16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage
Summary16,16-Dimethyl PGE2 (dmPGE2) has previously been shown to protect the in vivo rat liver against CCl4-induced damage. These… 
1984
1984
16,16-dimethyl-PGE2 protection against alpha-naphthylisothiocyanate-induced experimental cholangitis in the rat.
Male rats were treated with subcutaneous vehicle or 16,16-dimethyl-PGE2 (dmPGE2, 100 micrograms per kg), 24, 18 and 0.5 hr prior… 
1983
1983
Effect of 16,16-dimethyl prostaglandin E2 and ethanol on the constituents of gastric mucus.
The effect of ethanol, 16,16-dimethyl prostaglandin E2 (DMPGE2), and ethanol after DMPGE2 pretreatment on the solubilization of… 
1979
1979
Permeability effects of the E2 prostaglandins on canine gastric mucosa.
The effects on gastric mucosal permeability (GMP) of the topical application and intravenous administration of prostaglandin E2… 
1978
1978
Effects of 16,16-dimethyl prostaglandin E2 on ion transport by isolated rabbit gastric mucosa and rat intestinal epithelial cells.
The actions of 16,16-dimethyl prostaglandin E2 (dmPGE2) were investigated on ion transport in in vitro rabbit fundic mucosa and…