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BackgroundNeuropsychiatric disorders are common forms of disability in humans. Despite recent progress in deciphering the… Expand Background Sex hormones and gonadotropins exert a wide variety of effects in physiological and pathological processes… Expand Inspired by the localization, on 15q21.2 of the CYP19A1 gene in the linkage region of speech and language disorders, and a rare… Expand Senescence is a mechanism that limits cellular lifespan and constitutes a barrier against cellular immortalization. To identify… Expand CONTEXT
Aromatase excess syndrome (AES) is a rare hereditary autosomal dominant disorder characterized by increased… Expand The human CYP19 (p450arom) gene is located in the 21.2 region on the long arm of chromosome 15 (15q21.2). This gene spans a… Expand The human CYP19 (P450arom) gene is located in the chromosome 15q21.2 region and is comprised of a 30 kb coding region and a 93 kb… Expand BACKGROUND
Gynecomastia of prepubertal onset may result from increased estrogen owing to excessive aromatase activity in… Expand Cytochrome P-450 aromatase (P450arom), the key enzyme for estrogen biosynthesis, is encoded by a single gene, namely the CYP19… Expand By GenBank database searches and PCR, we have identified a novel human Bcl2-like gene, Bcl2-L-10, which contains conserved BH4… Expand