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15-Hydroxyprostaglandin dehydrogenase (NAD+)

Known as: prostaglandin-15-hydroxydehydrogenase, 15-ketoprostaglandin reductase, 15-PGDH 
 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

15-Hydroxyprostaglandin Dehydrogenase [NAD+], human
HPGD geneHPGD wt Allele

Broader (1)

Hydroxyprostaglandin Dehydrogenases

Papers overview

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2016
2016
Arabidopsis aldehyde dehydrogenase 10 family members confer salt tolerance through putrescine-derived 4-aminobutyrate (GABA) production
Polyamines represent a potential source of 4-aminobutyrate (GABA) in plants exposed to abiotic stress. Terminal catabolism of… Expand
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2014
2014
miR-21 Targets 15-PGDH and Promotes Cholangiocarcinoma Growth
miRNAs are a group of small, noncoding RNAs that modulate the translation of genes by binding to specific target sites in the… Expand
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2010
2010
UV Radiation Inhibits 15-Hydroxyprostaglandin Dehydrogenase Levels in Human Skin: Evidence of Transcriptional Suppression
Elevated levels of prostaglandins (PG) have been detected in the skin following UV radiation (UVR). PGs play an important role in… Expand
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2010
2010
Stimulation of reductive glycerol metabolism by overexpression of an aldehyde dehydrogenase in a recombinant Klebsiella pneumoniae strain defective in the oxidative pathway
Previously, we constructed a glycerol oxidative pathway-deficient mutant strain of Klebsiella pneumoniae by inactivation of… Expand
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2008
2008
Expression of 15-PGDH is downregulated by COX-2 in gastric cancer.
To explore the proteins regulated by cyclooxygenase-2 (COX-2) in gastric cancer, the expression plasmid of COX-2siRNA was… Expand
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Highly Cited
2005
Highly Cited
2005
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer.
It has been reported that two inducible prostaglandin synthetic enzymes, cylooxygenase-2 (COX-2) and microsomal PGE synthase, are… Expand
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2003
2003
Crystal Structure of Thermotoga maritima α-Glucosidase AglA Defines a New Clan of NAD+-dependent Glycosidases*
Glycoside hydrolase family 4 represents an unusual group of glucosidases with a requirement for NAD+, divalent metal cations, and… Expand
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2001
2001
(S)-1-Phenylethanol dehydrogenase of Azoarcus sp. strain EbN1, an enzyme of anaerobic ethylbenzene catabolism
Abstract. The initial steps in the anaerobic oxidation of the aromatic hydrocarbon ethylbenzene by denitrifying bacteria are two… Expand
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1997
1997
Crystal structure of a ternary complex of D-2-hydroxyisocaproate dehydrogenase from Lactobacillus casei, NAD+ and 2-oxoisocaproate at 1.9 A resolution.
D-2-hydroxyisocaproate dehydrogenase (D-HicDH) from Lactobacillus casei is a homodimer with 333 amino acids and a molecular mass… Expand
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1991
1991
Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme.
NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a key enzyme involved in the biological inactivation of the… Expand
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