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Hepatitis B (HBV) virus infects the liver, and upon chronic infection, can cause liver cirrhosis and hepatocellular carcinoma… (More)

Translational evaluation of disease progression and treatment response is critical to the development of therapies for… (More)

We examined the functional implication of nucleolin in the mouse first molar development. Both the nucleolin mRNA and protein… (More)

Inhalation of Bacillus anthracis, a bioterrorism agent, results in a high mortality rate despite appropriate antibiotic therapy… (More)

Immunostimulatory CpG-C oligodeoxyribonucleotides (ISS-ODNs) represent a promising strategy to enhance vaccine efficacy. We have… (More)

While effective for the prevention and treatment of allergic rhinitis (AR) symptoms, currently available medications do not… (More)

Overexpression of the HER-2 correlates with drug-resistance and a poor prognosis in breast cancer, however the mechanism(s) of… (More)

Existing HER-2 targeted therapies for human head and neck cancers, usually administered in combination with chemotherapeutic… (More)

BACKGROUND The failure to respond to chemotherapy is a major obstacle in the successful treatment of breast cancer. We have… (More)

Angiotensin II (Ang II) up-regulates plasminogen-activator inhibitor type-1 (PAI-1) expression in mesangial cells to enhance… (More)