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1-methylpseudouridine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-beta-D-ribofuranosyl- 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Pseudouridine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
The increasing importance of in vitro-transcribed (IVT) mRNA for synthesizing the encoded therapeutic protein in vivo demands the… Expand
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2019
2019
Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response
T cells made with messenger RNA (mRNA) encoding chimeric antigen receptor (CAR) offer a safe alternative to those transduced with… Expand
Review
2017
Review
2017
Nucleoside Modified mRNA Vaccines for Infectious Diseases.
In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune responses against… Expand
Highly Cited
2015
Highly Cited
2015
Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.
In recent years, in vitro transcribed messenger RNA (mRNA) has emerged as a potential therapeutic platform. To fulfill its… Expand
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2012
2012
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.
The methylation of pseudouridine (Ψ) at position 54 of tRNA, producing m(1)Ψ, is a hallmark of many archaeal species, but the… Expand
Highly Cited
1995
Highly Cited
1995
A novel enzymatic pathway leading to 1-methylinosine modification in Haloferax volcanii tRNA.
Transfer RNAs of the extreme halophile Haloferax volcanii contain several modified nucleosides, among them 1-methylpseudouridine… Expand
1982
1982
Structure of a modified nucleoside in archaebacterial tRNA which replaces ribosylthymine. 1-Methylpseudouridine.
The structure of a modified nucleoside isolated from Halococcus morrhuae tRNA has been established as 1-methylpseudouridine… Expand
1978
1978
Biosynthesis of a hypermodified nucleotide in Saccharomyces carlsbergensis 17S and HeLa-cell 18S ribosomal ribonucleic acid.
The biosynthesis of a hypermodified nucleotide, similar to or identical with 3-(3-amino-3-carboxypropyl)-1-methylpseudouridine… Expand
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1976
1976
1-methylpseudouridine, a metabolite of Streptomyces platensis.
1-Methylpseudouridine is a new metabolite isolated from culture filtrates of Streptomyces platensis. The structure of this… Expand
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