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1-methylpseudouridine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-beta-D-ribofuranosyl- 
 
National Institutes of Health

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Broader (1)

Pseudouridine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
N 1-Methylpseudouridine substitution enhances the performance of synthetic mRNA switches in cells
Synthetic messenger RNA (mRNA) tools often use pseudouridine and 5-methyl cytidine as substitutions for uridine and cytidine to… Expand
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2019
2019
A Facile Method for the Removal of dsRNA Contaminant from In Vitro-Transcribed mRNA
The increasing importance of in vitro-transcribed (IVT) mRNA for synthesizing the encoded therapeutic protein in vivo demands the… Expand
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2019
2019
Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response
T cells made with messenger RNA (mRNA) encoding chimeric antigen receptor (CAR) offer a safe alternative to those transduced with… Expand
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Review
2017
Review
2017
Nucleoside Modified mRNA Vaccines for Infectious Diseases.
In recent years, numerous studies have demonstrated the outstanding abilities of mRNA to elicit potent immune responses against… Expand
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Highly Cited
2015
Highly Cited
2015
Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes.
In recent years, in vitro transcribed messenger RNA (mRNA) has emerged as a potential therapeutic platform. To fulfill its… Expand
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2012
2012
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.
The methylation of pseudouridine (Ψ) at position 54 of tRNA, producing m(1)Ψ, is a hallmark of many archaeal species, but the… Expand
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1995
1995
A novel enzymatic pathway leading to 1-methylinosine modification in Haloferax volcanii tRNA.
Transfer RNAs of the extreme halophile Haloferax volcanii contain several modified nucleosides, among them 1-methylpseudouridine… Expand
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1982
1982
Structure of a modified nucleoside in archaebacterial tRNA which replaces ribosylthymine. 1-Methylpseudouridine.
The structure of a modified nucleoside isolated from Halococcus morrhuae tRNA has been established as 1-methylpseudouridine… Expand
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1978
1978
Biosynthesis of a hypermodified nucleotide in Saccharomyces carlsbergensis 17S and HeLa-cell 18S ribosomal ribonucleic acid.
The biosynthesis of a hypermodified nucleotide, similar to or identical with 3-(3-amino-3-carboxypropyl)-1-methylpseudouridine… Expand
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1976
1976
1-methylpseudouridine, a metabolite of Streptomyces platensis.
1-Methylpseudouridine is a new metabolite isolated from culture filtrates of Streptomyces platensis. The structure of this… Expand
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