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1-isoamyl-3-isobutylxanthine

Known as: 1H-Purine-2,6-dione, 3,7-dihydro-1-(3-methylbutyl)-3-(2-methylpropyl)-, 3-isobutyl-1-isoamylxanthine 
 
National Institutes of Health

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Related topics

2 relations

Broader (1)

1-Methyl-3-isobutylxanthine
analogs & derivatives

Papers overview

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1999
1999
Mechanism involved in synergistic adrenocorticotropin response to activating protein kinase-A and -C in rat anterior pituitary cells.
Activation of protein kinase C (PKC) stimulates adrenocorticotropin (ACTH) release synergistically in the presence of… Expand
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1990
1990
Activities of caffeine, theophylline, and enprofylline analogs as tracheal relaxants.
A variety of xanthines cause tracheal relaxation, an activity predictive of antiasthmatic potential. Structural analogs of… Expand
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Highly Cited
1989
Highly Cited
1989
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
The effects of 8-phenyl and 8-cycloalkyl substituents on the activity of theophylline, caffeine, 1,3-dipropylxanthine, 1,3… Expand
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1986
1986
Inhibition of cyclic nucleotide phosphodiesterases from pig coronary artery by benzo-separated analogues of 3-isobutyl-1-methylxanthine.
The linear and proximal benzo-separated analogues of 7-benzyl-3-isobutyl-1-methylxanthine, 3-isobutyl-1,8-dimethylxanthine, 3… Expand
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Highly Cited
1985
Highly Cited
1985
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
A series of 8-(substituted phenyl) derivatives of theophylline and other 1,3-dialkylxanthines were evaluated for potency and… Expand
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1985
1985
Stimulation by proctolin of the ouabain-insensitive sodium efflux in single barnacle muscle fibers.
  • J. Nwoga, E. Bittar
  • Comparative biochemistry and physiology. C…
  • 1985
    • Corpus ID: 10895823
A study has been made of the action of the neuropeptide proctolin on the radiosodium efflux from single barnacle muscle fibers… Expand
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1984
1984
The effects of alkylated xanthines on cyclic AMP accumulation in dog thyroid slices exposed to carbamylcholine.
In dog thyroid slices stimulated by thyrotropin (TSH), activation of muscarinic cholinergic receptors leads to a decrease in… Expand
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1982
1982
The role of cyclic nucleotide phosphodiesterase in the inhibition of cyclic AMP accumulation by carbachol and phosphatidate.
The possibility that activation of cyclic 3':5'-nucleotide phosphodiesterase is a component of muscarinic inhibition of cyclic… Expand
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Highly Cited
1979
Highly Cited
1979
Alkylxanthines: inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity.
Abstract A series of 1, 3-dialkylxanthines was examined as antagonists of adenosine-induced accumulation of cyclic AMP in guinea… Expand
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1979
1979
1-Isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic AMP in brain slices.
Abstract 1-Isoamyl-3-isobutylxanthine (EC50 t 5 μM) potentiates by 2 to 6-fold the accumulations of cyclic AMP elicited in guinea… Expand
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