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1-diphosphoinositol pentakisphosphate

Known as: 1-DPIPK, PP-IP(5), diphosphoinositol pentakisphosphate 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Inositol Phosphates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Akt/PKB activation and insulin signaling: a novel insulin signaling pathway in the treatment of type 2 diabetes
Type 2 diabetes is a metabolic disease categorized primarily by reduced insulin sensitivity, β-cell dysfunction, and elevated… Expand
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Highly Cited
2010
Highly Cited
2010
p53-mediated apoptosis requires inositol hexakisphosphate kinase-2
Inositol pyrophosphates have been implicated in numerous biological processes. Inositol hexakisphosphate kinase-2 (IP6K2), which… Expand
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Highly Cited
2008
Highly Cited
2008
HSP90 regulates cell survival via inositol hexakisphosphate kinase-2
Heat-shock proteins (HSPs) are abundant, inducible proteins best known for their ability to maintain the conformation of proteins… Expand
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Highly Cited
2007
Highly Cited
2007
Purification, Sequencing, and Molecular Identification of a Mammalian PP-InsP5 Kinase That Is Activated When Cells Are Exposed to Hyperosmotic Stress*
Mammalian cells utilize multiple signaling mechanisms to protect against the osmotic stress that accompanies plasma membrane ion… Expand
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Review
2005
Review
2005
Signalling: Friendly rivalry
  • K. Bussell
  • Nature Reviews Molecular Cell Biology
  • 2005
    • Corpus ID: 41016076
NATURE REVIEWS | MOLECULAR CELL BIOLOGY VOLUME 6 | FEBRUARY 2005 | 95 Move over kinases — a new way of phosphorylating has been… Expand
Highly Cited
2003
Highly Cited
2003
Inositol Pyrophosphates Mediate Chemotaxis in Dictyostelium via Pleckstrin Homology Domain-PtdIns(3,4,5)P3 Interactions
Inositol phosphates are well-known signaling molecules, whereas the inositol pyrophosphates, such as diphosphoinositol… Expand
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2003
2003
Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5"'-P1,P5-pentaphosphate and diphosphoinositol…
Schizosaccharomyces pombe Aps1 is an enzyme that degrades both diadenosine oligophosphates (Ap(n)A, n =5 or 6) and… Expand
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Highly Cited
2001
Highly Cited
2001
GRAB: A Physiologic Guanine Nucleotide Exchange Factor for Rab3a, which Interacts with Inositol Hexakisphosphate Kinase
Diphosphoinositol-pentakisphosphate (InsP7) and bis-diphosphoinositol tetrakisphosphate (InsP8) possess pyrophosphate bonds… Expand
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Highly Cited
1999
Highly Cited
1999
Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases
Inositol (1,4,5) trisphosphate (Ins(1,4,5)P(3)) is a well-known messenger molecule that releases calcium from intracellular… Expand
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1998
1998
Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate.
Diphosphoinositol pentakisphosphate (PP-IP5) and bis(diphospho)inositol tetrakisphosphate (bis-PP-IP4) were recently identified… Expand
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