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1-alkylglycerophosphocholine O-acetyltransferase activity

Known as: acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity, acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity, 1-alkyl-2-lysolecithin acetyltransferase activity 
Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA. [EC:2.3.1.67… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Radiation-induced increased platelet-activating factor activity in mixed saliva.
BACKGROUND Platelet-activating factor (PAF), a family of structurally-related phospholipid mediators of inflammation, is present… Expand
Highly Cited
1989
Highly Cited
1989
The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C.
Endothelial cells (EC) synthesize platelet-activating factor (PAF) when stimulated with agonists that bind to cell-surface… Expand
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1987
1987
Species-specific variations in the molecular heterogeneity of the platelet-activating factor.
The molecular heterogeneity of platelet-activating factor (PAF) synthesized by unstimulated and Ca2+ ionophore (A23187… Expand
Highly Cited
1986
Highly Cited
1986
Cytotoxicity and metabolism of alkyl phospholipid analogues in neoplastic cells.
The cytotoxic response of several types of neoplastic cells to analogues of unnatural alkyl phospholipids (e.g., rac-1-hexadecyl… Expand
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1986
1986
Effects of beta-adrenergic stimulation on 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine-mediated vasoconstriction and glycogenolysis in the perfused rat liver.
The beta-adrenergic agonist isoproterenol inhibited the glycogenolytic response of platelet-activating factor (AGEPC, 1-O… Expand
1986
1986
Ether phospholipids as inhibitors of the arachidonoyl-CoA: 1-acyl-sn-glycero-3-phosphocholine acyltransferase in macrophages.
1-Alkylglycerophosphatide analogs which are known to activate macrophages to enhanced tumor cytotoxicity are structurally closely… Expand
Highly Cited
1985
Highly Cited
1985
Acylation of lysophospholipids by rabbit alveolar macrophages. Specificities of CoA-dependent and CoA-independent reactions.
Intact alveolar macrophages were found to acylate alkyl- and acyllysophospholipids with a high selectivity for arachidonate. A… Expand
1985
1985
Phospholipid biosynthesis in human platelets. The acylation of lyso-platelet-activating factor.
Acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase of human platelets is membrane-bound, has a pH optimum of 7.5, is… Expand
Highly Cited
1984
Highly Cited
1984
Increased biosynthesis of platelet-activating factor in activated human eosinophils.
1-Alkyl-2-lyso-sn-glycero-3-phosphocholine:acetyl-CoA acetyltransferase catalyzes the conversion of biologically inactive… Expand
Highly Cited
1980
Highly Cited
1980
Enzymatic synthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, a hypotensive and platelet-aggregating lipid.
1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine, derived chemically from choline plasmalogens of beef heart, has been shown to… Expand
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