1-Acylglycerophosphocholine O-Acyltransferase

Known as: Lysophosphatidylcholine-Palmitoyl CoA Acyltransferase, Acyl-CoA-1-Acylglycero-3-Phosphocholine-O-Acyltransferase, Acyltransferase, Lysophospholipid 
An enzyme localized predominantly within the plasma membrane of lymphocytes. It catalyzes the transfer of long-chain fatty acids, preferentially… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2017
05019632017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Triacylglycerol (TAG) biosynthesis is a principal metabolic pathway in most organisms, and TAG is the major form of carbon… (More)
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Highly Cited
2005
Highly Cited
2005
In this study, we investigated the role of acyl-coenzyme A:diacylglycerol acyltransferase 2 (DGAT2) in glucose and lipid… (More)
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Highly Cited
2004
Highly Cited
2004
Lecithin-retinol acyltransferase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts… (More)
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Highly Cited
2004
Highly Cited
2004
Amyloid beta-peptide (Abeta) accumulation in specific brain regions is a pathological hallmark of Alzheimer's disease (AD). We… (More)
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Highly Cited
2000
Highly Cited
2000
The transmembrane protein CD36 has been identified in isolated cell studies as a putative transporter of long chain fatty acids… (More)
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Highly Cited
1998
Highly Cited
1998
The enzyme acyl coenzyme A:cholesterol acyltransferase 1 (ACAT1) mediates sterol esterification, a crucial component of… (More)
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Highly Cited
1997
Highly Cited
1997
Previous studies from this laboratory have demonstrated that exposure of tissue culture cells to cyclodextrins results in rapid… (More)
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Highly Cited
1993
Highly Cited
1993
Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic… (More)
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Highly Cited
1984
Highly Cited
1984
Studies in ischemic canine left ventricle have shown that the depletion of membrane phospholipids is a critical event in the… (More)
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Highly Cited
1979
Highly Cited
1979
Mouse peritoneal macrophages accumulate large amounts of cholesteryl ester when incubated with human low-density lipoprotein that… (More)
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