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1-(2-pyrimidinyl)piperazine

National Institutes of Health

Papers overview

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2002
2002
The objective of this investigation was to compare the in vivo potency and intrinsic activity of buspirone and its metabolite 1… 
1998
1998
Abstract Biotransformation of gepirone to its principal metabolite, 1-(2-pyrimidinyl)-piperazine (1-PP), was studied in human… 
1992
1992
Tandospirone is an azaspirodecanedione derivative under investigation as an antidepressant. Metabolism of tandospirone in humans… 
Highly Cited
1989
Highly Cited
1989
  • R. FullerK. Perry
  • The Journal of pharmacology and experimental…
  • 1989
  • Corpus ID: 24981907
Buspirone, an anxiolytic drug with selective affinity for the 5-HT-1A subtype of serotonin receptors, caused a dose-related… 
1989
1989
Pyrimidinylpiperazine anxiolytic drugs-ipsapirone, buspirone and gepirone-dose- dependently increased punished responding in an… 
Highly Cited
1983
Highly Cited
1983
After i.v. injection (10 mg/kg) to rats, buspirone is rapidly cleared from blood with a t1/2 (beta) or 30 min. After the same…