1-(2-pyrimidinyl)piperazine

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
02419822017

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2002
2002
The objective of this investigation was to compare the in vivo potency and intrinsic activity of buspirone and its metabolite 1… (More)
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2001
2001
The conformational of selected 1-(2-pyrimidinyl)piperazine derivatives with high sedative-hypnotic activity was analysed and the… (More)
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1995
1995
The effects of acute and repeated treatment with 1-(2-pyrimidinyl)piperazine (1-PP), a metabolite of the 5-HT1A receptor ligand… (More)
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1992
1992
A selective and sensitive high-performance liquid chromatographic method with coulometric detection is described for the… (More)
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1992
1992
Using a standard two-lever operant procedure with rats trained to discriminate 1-(3-trifluoromethylphenyl)piperazine (TFMPP) (0.5… (More)
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1990
1990
The effect of 1-(2-pyrimidinyl)piperazine (PmP), the main metabolite of buspirone, was tested on K(+)-evoked [3H]noradrenaline… (More)
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1989
1989
Buspirone, an anxiolytic drug with selective affinity for the 5-HT-1A subtype of serotonin receptors, caused a dose-related… (More)
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1989
1989
Pyrimidinylpiperazine anxiolytic drugs-ipsapirone, buspirone and gepirone-dose- dependently increased punished responding in an… (More)
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1989
1989
In experiments on rats the anxiolytic activity of 1-(2-pyrimidinyl)-piperazine (PP) was revealed only in some models of anxiety… (More)
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1988
1988
Buspirone and a buspirone metabolite, 1-(2-pyrimidinyl)piperazine (1-PP), are extracted from matrix using C18 extraction columns… (More)
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