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1,7-dimethylxanthine

Known as: 3,7-dihydro-1,7-dimethyl-1H-purine-2,6- dione, paraxanthine 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Theophylline

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Effect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patients.
Clozapine and caffeine are metabolised mainly by the cytochrome P4501A2 (CYP1A2) enzyme. Studies suggest that caffeine in coffee… 
Highly Cited
2001
Highly Cited
2001
Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer.
Highly Cited
2000
Highly Cited
2000
Evaluation of the Influence of Diabetes Mellitus on Antipyrine Metabolism and CYP1A2 and CYP2D6 Activity
Study Objective. To evaluate the metabolism of antipyrine, a general metabolic probe, caffeine, a probe for cytochrome P450 (CYP… 
1997
1997
Impact of long‐term ethanol consumption on CYP1A2 activity
1995
1995
Microdialysis sampling coupled on-line to fast microbore liquid chromatography.
1990
1990
Override of the radiation-induced mitotic block in human tumour cells by methylxanthines and its relationship to the potentiation of cytotoxicity.
The four methylated xanthine derivatives, caffeine, theophylline, theobromine and paraxanthine, were tested for their ability to… 
Highly Cited
1988
Highly Cited
1988
Caffeine and theophylline metabolism in newborn and adult human hepatocytes; comparison with adult rat hepatocytes.
Highly Cited
1987
Highly Cited
1987
An alternative test for acetylator phenotyping with caffeine
Previously published methods allow the determination of the genetically controlled acetylator status using caffeine as a test… 
Highly Cited
1985
Highly Cited
1985
Variability of caffeine metabolism in humans.
The metabolic disappearance of caffeine from blood is subject to substantial inter- and intra-individual variation. Smoking of… 
1974
1974
Structure‐activity relations for caffeine: a comparative study of the inotropic effects of the methylxanthines, imidazoles and related compounds on the frog's heart
1. The ability of several groups of compounds, related to caffeine, to induce contractures in isolated frog auricular trabeculae… 
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