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1,10-bis(carboxymethylthiodecane)

Known as: BCMTD, 3-thiadicarboxylic acid, 1,10-bis(carboxymethylthio)decane 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Dicarboxylic AcidsSulfides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Early modulation of genes encoding peroxisomal and mitochondrial beta-oxidation enzymes by 3-thia fatty acids.
The aim of the present study was to elucidate the effects of a single dose of 3-thia fatty acids (tetradecylthioacetic acid and 3… Expand
1995
1995
Acute modulation of rat hepatic lipid metabolism by sulphur-substituted fatty acid analogues.
A single oral dose of two 3-thia (3-thiadicarboxylic and tetradecylthioacetic acids) and of 4-thia (tetradecylthiopropionic acid… Expand
1995
1995
Fatty acyl-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rat treated with peroxisome proliferating 3-thia fatty acids.
1. In this study we explored the relationship between specific acyl-CoA esters and induction of acyl-CoA binding protein (ACBP… Expand
Highly Cited
1993
Highly Cited
1993
On the mechanism of the hypolipidemic effect of sulfur-substituted hexadecanedioic acid (3-thiadicarboxylic acid) in normolipidemic rats.
The mechanism behind the hypolipidemic effect of the sulfur-substituted non-beta-oxidizable fatty acid analogue 1,10 bis… Expand
Highly Cited
1991
Highly Cited
1991
Peroxisome proliferating sulphur- and oxy-substituted fatty acid analogues are activated to acyl coenzyme A thioesters.
In liver homogenates from untreated rats the sulphur-substituted fatty acid analogues tetradecylthioacetic acid (CMTTD) was… Expand
Highly Cited
1990
Highly Cited
1990
Regulation of fatty acid oxidation and triglyceride and phospholipid metabolism by hypolipidemic sulfur-substituted fatty acid analogues.
The mechanisms behind the hypotriglyceridemic effect of 1,10-bis(carboxymethylthio)decane (3-thiadicarboxylic acid) and… Expand
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1990
1990
Fatty acid metabolism in liver of rats treated with hypolipidemic sulphur-substituted fatty acid analogues.
The purpose of this study was to investigate early biochemical changes and possible mechanisms via which alkyl(C12)thioacetic… Expand
1990
1990
Morphologic effects of sulfur-substituted fatty acids on rat hepatocytes with special reference to proliferation of peroxisomes and mitochondria.
The morphologic effects of different sulfur-substituted mono- and dicarboxylic fatty acids on rat hepatocytes have been examined… Expand
Highly Cited
1989
Highly Cited
1989
Alkylthioacetic acids (3-thia fatty acids) as non-beta-oxidizable fatty acid analogues: a new group of hypolipidemic drugs. III. Dissociation of cholesterol- and triglyceride-lowering effects and the…
Previous work in this laboratory indicated that sulfur-substituted fatty acid analogues, 1.10-bis(carboxymethylthio)decane and… Expand
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Highly Cited
1989
Highly Cited
1989
Alkylthio acetic acids (3-thia fatty acids)--a new group of non-beta-oxidizable peroxisome-inducing fatty acid analogues--II. Dose-response studies on hepatic peroxisomal- and mitochondrial changes…
The activity of key enzymes involved in oxidation and esterification of long-chain fatty acids was investigated after male Wistar… Expand
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